Department of Pediatrics, Division of Pediatric Cardiology, University of Alberta and Stollery Children's Hospital, Edmonton, Alberta, Canada.
J Am Soc Echocardiogr. 2010 Mar;23(3):286-93. doi: 10.1016/j.echo.2009.11.018. Epub 2010 Jan 25.
Left ventricular (LV) torsion and untwisting are important components of LV performance, but there is little information on the effect of age, particularly in younger populations.
LV rotation and LV rotation rate, torsion, recoiling, and untwisting were measured in normal subjects (n=111) aged 3 to 40 years (mean age, 19.3 years) using speckle-tracking imaging.
LV torsion increased with age because of the augmentation of apical LV rotation, but this disappeared when normalized by LV length. Although peak LV torsion and apical LV rotation increased with age, the normalized peak torsion rate decreased. As well, the peak untwisting rate decreased with age and was enhanced when normalized by LV length. Younger hearts demonstrated greater untwisting and recoiling of the apex during isovolumic relaxation and early diastole. The time difference between apical and basal events decreased with advancing age.
The heart maintains a constant LV torsion and LV rotation profile when normalized by length and cardiac cycle. Younger hearts tend to twist, untwist, and deform faster.
左心室（LV）扭转和解旋是 LV 功能的重要组成部分，但关于年龄的影响，特别是在年轻人群中的信息较少。
使用斑点追踪成像技术，在年龄为 3 至 40 岁（平均年龄为 19.3 岁）的正常受试者（n=111）中测量 LV 旋转和 LV 旋转率、扭转、回弹和解旋。
由于心尖 LV 旋转的增加，LV 扭转随年龄而增加，但通过 LV 长度标准化后，这种增加就消失了。尽管峰值 LV 扭转和心尖 LV 旋转随年龄增加，但标准化的峰值扭转率降低。同样，峰值解旋率随年龄而降低，并且通过 LV 长度标准化后会增强。年轻的心脏在等容舒张和早期舒张期间表现出更大的心尖解旋和回弹。心尖和基底事件之间的时间差随着年龄的增长而减小。
当通过长度和心动周期标准化时，心脏保持恒定的 LV 扭转和 LV 旋转曲线。年轻的心脏往往会更快地扭转、解旋和变形。
