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麻痹性贝类中毒时肌酸激酶MB升高

Creatine kinase MB elevation in paralytic shellfish poisoning.

作者信息

Cheng H S, Chua S O, Hung J S, Yip K K

机构信息

Department of Medicine, Chang Gung Memorial Hospital, Taipei, Taiwan, Republic of China.

出版信息

Chest. 1991 Apr;99(4):1032-3. doi: 10.1378/chest.99.4.1032.

DOI:10.1378/chest.99.4.1032
PMID:2009759
Abstract

An outbreak of paralytic shellfish poisoning occurred in southern Taiwan, affecting 116 persons who had consumed purple clams. Two victims died within four hours. Gonyautoxins were identified as causative toxins. During the outbreak, five patients with paralytic shellfish poisoning were seen in our hospital. All recovered following supportive treatments. Serum creatine kinase concentration was elevated in three of the five patients. The levels of the enzyme did not seem to correlate with the severity of poisoning. The most significant finding was the previously unreported observation of elevation of the creatine kinase MB level. In all four patients who had creatine kinase MB value determined, it was elevated.

摘要

台湾南部发生了一起麻痹性贝类中毒事件,116名食用紫蛤的人受到影响。两名受害者在4小时内死亡。已确定冈田毒素为致病毒素。疫情期间,我院收治了5例麻痹性贝类中毒患者。所有患者经支持治疗后均康复。5例患者中有3例血清肌酸激酶浓度升高。该酶水平似乎与中毒严重程度无关。最显著的发现是肌酸激酶MB水平升高这一此前未报告的观察结果。在所有4例测定了肌酸激酶MB值的患者中,该值均升高。

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