Yang K L, Dantzker D R
Division of Pulmonary and Critical Care Medicine, University of Texas Health Science Center, Houston.
Chest. 1991 Apr;99(4):1037-8. doi: 10.1378/chest.99.4.1037.
Tricyclic antidepressants are known to cause central nervous system depression. However, a generalized depression of brainstem functions is rarely reported. We report a patient in deep coma with complete absence of brain-stem reflexes after she had taken a large quantity of amitriptyline. With continuous supportive treatment, she eventually regained all neurologic function and made a full recovery.
三环类抗抑郁药已知会导致中枢神经系统抑制。然而，脑干功能的全身性抑制鲜有报道。我们报告一例患者，她服用大量阿米替林后陷入深度昏迷，脑干反射完全消失。经过持续的支持治疗，她最终恢复了所有神经功能并完全康复。
