Rakotoarivelo R A, Razafimahefa S H, Andrianiaina H D, Randria M J D
Service des maladies infectieuses, hôpital Joseph-Raseta-Befelatanana, CHU d'Antananarivo, Madagascar.
Bull Soc Pathol Exot. 2010 Feb;103(1):19-21. doi: 10.1007/s13149-009-0030-7. Epub 2010 Jan 22.
African histoplasmosis is a rare but not an exceptional condition and recently discovered in Madagascar. We report the fifth Malagasy case involving skin and nodes in an immunocompetent patient. Management of African histoplasmosis encountered many problems because of the availability of amphotericin B and cost of the biochemical tests in order to prevent major side effects in case of failure of oral antimycotic drug.
非洲组织胞浆菌病较为罕见但并非特殊病症，最近在马达加斯加被发现。我们报告了第五例马达加斯加病例，该病例发生在一名免疫功能正常的患者身上，累及皮肤和淋巴结。由于两性霉素B的可获得性以及生化检测的费用，非洲组织胞浆菌病的治疗遇到了许多问题，目的是在口服抗真菌药物治疗失败时预防严重的副作用。
