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[加蓬系统性红斑狼疮管理成本评估]

[Evaluation of the cost of managing systemic lupus erythematosus in Gabon].

作者信息

Iba-Ba J, Bignoumba Ibouili R, Moussavou Kombila J B, Coniquet S, Boguikouma J B

出版信息

Med Trop (Mars). 2009 Dec;69(6):631.

PMID:20099685
Abstract

The purpose of this retrospective study was to evaluate the cost of managing systemic lupus erythematosus in Gabon. Study was carried out from 01/2004 to 12/2007. All patients presenting at least 4 of the 11 diagnostic criteria of the American College of Rheumatology were included. The total cost was calculated for the first year and from the second year. A total of 25 patients (24 women, 1 man) with a mean age of 29.6 years (range: 18 and 45) were included in the study. Care was provided by the patient her/himself (n = 8), parents (n = 11), or jointly by other relatives (n = 6). The average cost of accommodation was euro 769.6. Diagnostic review and impact cost were euro 53.3 and euro 58.6 respectively. Overall the average cost of hospitalization was euro 972.7. The total cost for the first year following diagnosis was 1398.6 for patients with the cutaneous-articular form of systemic lupus erythematousus and euro 1500.7 for patients with visceral forms. From the second year on, the annual cost was euro 261 for patients with the cutaneous-articular form and euro 534.7 for patients with visceral forms. Sixteen of the 25 patients were regularly re-examined as outpatients. Nine patients were lost to follow-up including 5 during the first year, 3 during the second year, and 1 during the third year. Two deaths occurred due to chronic renal failure and septic shock. This study shows that long-term follow-up for systemic lupus erythematosus in Gabon is difficult due to patient dropout.

摘要

这项回顾性研究的目的是评估加蓬系统性红斑狼疮的管理成本。研究于2004年1月至2007年12月进行。纳入了所有符合美国风湿病学会11项诊断标准中至少4项的患者。计算了第一年和第二年的总成本。共有25名患者(24名女性,1名男性)纳入研究,平均年龄29.6岁(范围:18至45岁)。护理由患者本人(n = 8)、父母(n = 11)或其他亲属共同提供(n = 6)。住宿平均成本为769.6欧元。诊断复查和影响成本分别为53.3欧元和58.6欧元。总体而言,住院平均成本为972.7欧元。皮肤关节型系统性红斑狼疮患者诊断后第一年的总成本为1398.6欧元,内脏型患者为1500.7欧元。从第二年起,皮肤关节型患者的年度成本为261欧元,内脏型患者为534.7欧元。25名患者中有16名作为门诊患者定期复诊。9名患者失访,其中第一年5名,第二年3名,第三年1名。2例死亡,原因是慢性肾衰竭和感染性休克。这项研究表明,由于患者失访,加蓬系统性红斑狼疮的长期随访很困难。

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