Division of Otolaryngology, Head and Neck Surgery, Department of Surgery, Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina 27710, USA.
Otol Neurotol. 2010 Feb;31(2):190-5. doi: 10.1097/MAO.0b013e3181c9940c.
Practice-based research networks (PBRNs) are the preferred research setting for descriptive/epidemiologic studies and studies that explore the effectiveness of treatments for disease that are managed in community settings, away from the rubric of the academic medical center. A PBRN in otology/neurotology, established upon a sustainable research infrastructure, addresses the challenges of performing community-based research through enhanced support for data collection and facilitated research regulatory adherence. A strategic alignment of a PBRN with an established research infrastructure allows for successful implementation of a variety of study methodologies and a framework for successful competition for research funding in hearing and balance disorders. Our goal is to develop a centralized, high-quality research infrastructure that supports a dynamic research alliance between regional centers for research excellence, community physicians, allied health professionals, and patients.
We describe herein current plans and progress toward the goal of developing a network of academic- and community-based research sites to facilitate the conduct of clinical research in hearing and balance disorders. We have formed a PBRN that we call the CHEER Network: Creating Healthcare Excellence through Education and Research. Creating healthcare excellence through education and research was proposed in response to a request for applications from the National Institute for Deafness and other Communication Disorders to further develop clinical research in otolaryngology, specifically focusing on disorders in hearing and balance.
Our expectation is that a network organized and focused around regional research alliances between academic institutions and community practitioners will have broad appeal to community-based health care professionals and patients, resulting in enhanced communications, interoperability, and success in the conduct of high-quality multicenter clinical research in hearing and balance disorders.
实践为基础的研究网络（PBRN）是描述性/流行病学研究和探索在社区环境中管理的疾病治疗效果的首选研究环境，远离学术医疗中心的范畴。一个基于可持续研究基础设施的耳科学/神经耳科学 PBRN，通过增强数据收集的支持和促进研究监管遵守，解决了进行基于社区的研究的挑战。PBRN 与既定研究基础设施的战略对齐允许成功实施各种研究方法，并为听力和平衡障碍的研究资金成功竞争提供框架。我们的目标是开发一个集中的、高质量的研究基础设施，支持区域卓越研究中心、社区医生、联合健康专业人员和患者之间的动态研究联盟。
我们在此描述了目前计划和进展，以实现建立一个由学术和社区研究站点组成的网络的目标，以促进听力和平衡障碍的临床研究。我们已经成立了一个名为 CHEER Network 的 PBRN：通过教育和研究创造医疗保健卓越。通过教育和研究创造医疗保健卓越是为了响应国家耳聋和其他沟通障碍研究所的应用请求而提出的，旨在进一步发展耳鼻喉科的临床研究，特别是关注听力和平衡障碍。
我们期望一个围绕学术机构和社区从业者之间的区域研究联盟组织和集中的网络将对社区为基础的医疗保健专业人员和患者具有广泛的吸引力，从而增强沟通、互操作性，并成功开展高质量的多中心听力和平衡障碍临床研究。
