Oregon Rural Practice-based Research Network, Oregon Health & Science University, Portland, Oregon 97239-3098, USA.
Acad Med. 2010 Mar;85(3):476-83. doi: 10.1097/ACM.0b013e3181cd2ed3.
Practice-based research networks (PBRNs) are a part of many National Institutes of Health (NIH)-funded Clinical and Translational Science Award (CTSA) sites. PBRNs, groups of primary care practices committed to collaborating on practice-relevant research, are unfamiliar to many CTSA leaders. Conversely, the CTSAs, as new research structures designed to transform clinical research, are unfamiliar to many PBRN directors. This study examined the extent to which these programs have congruent goals and expectations, and whether their engagement is likely to be mutually beneficial.
The authors sent a Web-based survey to 38 CTSA community engagement directors and a similar survey to 114 PBRN directors during the fall of 2008.
A total of 66% (25/38) CTSA community engagement directors and 61% (69/114) PBRN directors responded. Two thirds of responding CTSAs reported working with PBRNs, and over half of responding PBRNs reported a CTSA affiliation. Both groups indicated this relationship was important. CTSAs looked to PBRNs for access to patients and expertise in engaging communities and clinical practices. PBRNs reported seeking stable infrastructure support and greater collaboration and visibility in the academic research community. PBRN infrastructure support from CTSAs was highly variable. Both groups perceived considerable promise for building sustainable relationships and a bidirectional flow of information and research opportunities.
With fewer than three years of experience, the PBRN/CTSA relationship remains in the discovery phase; the participants are still negotiating expectations. If these collaborations prove mutually beneficial, they may advance the community engagement goals of many academic health centers.
实践为基础的研究网络（PBRNs）是许多美国国立卫生研究院（NIH）资助的临床和转化科学奖（CTSA）基地的一部分。PBRNs 是由初级保健实践组成的团体，致力于合作开展与实践相关的研究，许多 CTSA 领导者对其并不熟悉。相反，CTSA 作为旨在改变临床研究的新研究结构，许多 PBRN 主任对其也不熟悉。本研究考察了这些计划在多大程度上具有一致的目标和期望，以及它们的参与是否可能相互有利。
作者在 2008 年秋季向 38 个 CTSA 社区参与主任发送了一份基于网络的调查，向 114 个 PBRN 主任发送了一份类似的调查。
共有 66%（25/38）的 CTSA 社区参与主任和 61%（69/114）的 PBRN 主任作出了回应。三分之二的回应 CTSA 报告与 PBRN 合作，超过一半的回应 PBRN 报告与 CTSA 有联系。这两个群体都表示这种关系很重要。CTSA 寻求 PBRN 获得患者和社区参与以及临床实践的专业知识。PBRN 报告寻求稳定的基础设施支持以及在学术研究界更大的合作和可见度。CTSA 对 PBRN 的基础设施支持差异很大。这两个群体都认为有很大的潜力建立可持续的关系，并实现信息和研究机会的双向流动。
在不到三年的时间里，PBRN/CTSA 关系仍处于发现阶段；参与者仍在协商期望。如果这些合作证明是互利的，它们可能会推进许多学术医疗中心的社区参与目标。
