Ertabaklar Hatice, Kivçak Bijen, Mert Tuba, Ozensoy Töz Seray
Adnan Menderes University Medical School, Department of Parasitology, Aydin, Turkey.
Turkiye Parazitol Derg. 2009;33(4):263-5.
Trichomonas vaginalis (T. vaginalis) is a flagellated protozoan commonly causing sexually transmitted disease. T. vaginalis infections are treated with a 5-nitroimidazole derivate. However, drug resistance has been known to occur for a long time and new alternatives are under investigation. Arbutus unedo is a wild plant mainly growing in maquis and rocky places of the seaboard in Southern Europe. In our study, ethanolic, water, hexane and ethyl acetate extracts of Arbutus unedo leaves were tested in vitro against T. vaginalis trophozoites and the ethyl acetate extract of Arbutus unedo leaves was found to be effective (Growth inhibition rate (GI): 100%, at the concentration of 500 microg/ml). It may be a promising anti-trichomonacidal agent in the future and further experiments are needed.
阴道毛滴虫是一种鞭毛虫原生动物，通常会引发性传播疾病。阴道毛滴虫感染采用5-硝基咪唑衍生物进行治疗。然而，耐药性早已出现，新的替代药物正在研究中。草莓树是一种野生植物，主要生长在欧洲南部沿海的马基群落和岩石地带。在我们的研究中，对草莓树叶的乙醇提取物、水提取物、己烷提取物和乙酸乙酯提取物进行了体外抗阴道毛滴虫滋养体测试，发现草莓树叶的乙酸乙酯提取物具有效果（生长抑制率（GI）：在浓度为500微克/毫升时为100%）。它未来可能是一种有前景的抗滴虫剂，还需要进一步实验。
