通过分子场拓扑分析（MFTA）研究O-磷酸化肟类化合物急性和迟发性神经毒性的结构决定因素。 - Suppr

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超能文献

Study of the structural determinants of acute and delayed neurotoxicity of O-phosphorylated oximes by molecular field topology analysis (MFTA).

作者信息

Radchenko E V, Makhaeva G F, Sokolov V B, Palyulin V A, Zefirov N S

机构信息

Moscow State University, Moscow, 119991 Russia.

出版信息

Dokl Biochem Biophys. 2009 Nov-Dec;429:309-14. doi: 10.1134/s1607672909060064.

DOI:10.1134/s1607672909060064

PMID:20101827

Abstract

摘要

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本文引用的文献

Esterase profile and analysis of structure-inhibitor selectivity relationships for homologous phosphorylated 1-hydroperfluoroisopropanols.同源磷酸化1-氢全氟异丙醇的酯酶谱及结构-抑制剂选择性关系分析

Dokl Biochem Biophys. 2008 Nov-Dec;423:352-7. doi: 10.1134/s1607672908060094.

Dokl Biochem Biophys. 2008 Jan-Feb;418:47-51. doi: 10.1134/s1607672908010122.

Quantitative structure-activity relationships predict the delayed neurotoxicity potential of a series of O-alkyl-O-methylchloroformimino phenylphosphonates.定量构效关系预测了一系列O-烷基-O-甲基氯亚氨基苯基膦酸酯的迟发性神经毒性潜力。

J Toxicol Environ Health A. 2003 Apr 11;66(7):611-25. doi: 10.1080/15287390309353770.

Assessment of the neurotoxic potential of some methyl- and phenylphosphonates using a stable preparation of neuropathy target esterase from chicken brain.利用鸡脑制备的稳定的神经病变靶酯酶评估某些甲基膦酸酯和苯基膦酸酯的神经毒性潜力。

Dokl Biochem Biophys. 2001 Mar-Apr;377:68-71. doi: 10.1023/a:1011515320263.

QSAR for the organophosphate-induced inhibition and 'aging' of the enzyme neuropathy target esterase (NTE).有机磷酸酯诱导的神经病变靶酯酶（NTE）抑制和“老化”的定量构效关系

SAR QSAR Environ Res. 2001;12(3):275-95. doi: 10.1080/10629360108032917.

Molecular field Topology analysis method in QSAR studies of organic compounds.有机化合物定量构效关系研究中的分子场拓扑分析方法。

J Chem Inf Comput Sci. 2000 May;40(3):659-67. doi: 10.1021/ci980114i.

Neurotoxicology. 1998 Aug-Oct;19(4-5):623-8.

Neuropathy target esterase (NTE) and organophosphorus-induced delayed polyneuropathy (OPIDP): recent advances.神经病靶酯酶（NTE）与有机磷诱导的迟发性多发性神经病（OPIDP）：最新进展

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