Babb T G, Korzick D, Meador M, Hodgson J L, Buskirk E R
Department of Medicine, Baylor College of Medicine, Houston, TX 77030.
Int J Obes. 1991 Jan;15(1):59-65.
To investigate the effect of moderate obesity on ventilatory responses to graded exercise, we compared the ventilatory responses of ten moderately obese (35 +/- 5 percent body fat) and nine leaner women (22 +/- 2 percent body fat) during walking on a treadmill with incremental increases in percent grade. Speed remained constant at 3.0 mph. In the obese women, VO2 in l/min and ml/FFW/min, fb (b/min), VE (l/min), and HR were significantly greater (P less than 0.05) at all four absolute workloads. At 10.0 and 12.5 percent grade, VO2 (ml/kg/min) was smaller and VE/VO2 was greater in the obese women. The difference in VE/VO2 suggests a lower ventilatory threshold for the obese women. Percent VO2 max and R (VCO2/VO2) were significantly different at 12.5 percent grade only. When VO2 was divided by HR (oxygen pulse), the two groups were not significantly different at any of the four workloads tested. The groups were compared further at workloads representing approximately 55, 65, 75, and 85 percent of VO2 max. HR was not significantly different at any of the four relative exercise intensities. VE was significantly greater in the obese at 85 percent of maximum only (P less than 0.05) and fb was significantly greater at 55, 75, and 85 percent of maximum. Whereas cardiorespiratory responses of moderately obese women are increased at absolute workloads when compared to that of leaner women, HR is similar at comparable intensities of exercise. VE is also similar at comparable intensities of exercise below ventilatory threshold but fb is greater. The effect of the higher fb on exercise tolerance is unknown.(ABSTRACT TRUNCATED AT 250 WORDS)
为研究中度肥胖对分级运动通气反应的影响，我们比较了10名中度肥胖女性（体脂率35±5%）和9名较瘦女性（体脂率22±2%）在跑步机上行走时的通气反应，坡度百分比逐渐增加。速度保持在3.0英里/小时恒定。在所有四个绝对工作量下，肥胖女性的每分钟升氧量（VO2，单位：l/min和ml/FFW/min）、呼吸频率（fb，单位：b/min）、每分通气量（VE，单位：l/min）和心率（HR）均显著更高（P<0.05）。在坡度为10.0%和12.5%时，肥胖女性的VO2（单位：ml/kg/min）较小，VE/VO2较大。VE/VO2的差异表明肥胖女性的通气阈值较低。仅在坡度为12.5%时，最大摄氧量百分比（Percent VO2 max）和呼吸商（R，VCO2/VO2）存在显著差异。当用VO2除以HR（氧脉搏）时，在测试的四个工作量中的任何一个下，两组均无显著差异。在代表最大摄氧量约55%、65%、75%和85%的工作量下对两组进行了进一步比较。在四个相对运动强度中的任何一个下，心率均无显著差异。仅在最大强度的85%时，肥胖女性的每分通气量显著更大（P<0.05），在最大强度的55%、75%和85%时，呼吸频率显著更高。与较瘦女性相比，中度肥胖女性在绝对工作量下的心肺反应增加，但在相当的运动强度下心率相似。在低于通气阈值的相当运动强度下，每分通气量也相似，但呼吸频率更高。较高的呼吸频率对运动耐力的影响尚不清楚。（摘要截选至250字）
