Wolter M, Schleussner-Samuel P, Marsch W C
Abteilung, Zentrum der Dermatologie und Venerologie, Johann Wolfgang Goethe-Universität Frankfurt am Main.
Hautarzt. 1991 Jan;42(1):50-2.
A 34-year-old woman presented with leathery thickening and haemorrhagic lesions of several finger- and toe-nails as first symptoms of an HTLV-I infection. Histology resembled that found in mycosis fungoides. Later signs of T cell deficiency (e.g. Pneumocystis carinii pneumonia) developed. An erythemato-papular exanthema representing T cell lymphoma with Pautrier's abscesses preceded her death 1 year later. The detection of HTLV-I antibodies helped to establish the diagnosis following initial confusion owing to elevation of the T-helper cells and the CD4/CD8 ratio.
一名34岁女性出现数枚手指甲和脚趾甲的皮革样增厚及出血性损害，这是HTLV-I感染的首发症状。组织学表现类似于蕈样肉芽肿。随后出现T细胞缺陷的体征（如卡氏肺孢子虫肺炎）。1年后，在她死亡前出现了表现为T细胞淋巴瘤伴鲍特利尔脓肿的红斑丘疹性皮疹。由于辅助性T细胞及CD4/CD8比值升高导致最初诊断混淆，而HTLV-I抗体的检测有助于确诊。
