Kraemer W J, Patton J F, Knuttgen H G, Hannan C J, Kettler T, Gordon S E, Dziados J E, Fry A C, Frykman P N, Harman E A
Exercise Physiology Division, US Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760-5007.
J Appl Physiol (1985). 1991 Jan;70(1):8-14. doi: 10.1152/jappl.1991.70.1.8.
Plasma proenkephalin peptide F immunoreactivity and catecholamines were examined on separate days in nine healthy males before and after maximal exercise to exhaustion at four intensities [36, 55, 73, and 100% of maximal leg power (MLP)] by use of a computerized cycle ergometer. The mean duration of 36, 55, 73, and 100% MLP was 3.31, 0.781, 0.270, and 0.1 min, respectively. All intensities were greater than those eliciting peak O2 uptake for the individual subjects. Blood samples were obtained before, immediately after exercise, and 5 and 15 min after exercise. Significant (P less than 0.05) increases in plasma peptide F immunoreactivity (i.e., from mean resting value of 0.18 to 0.43 pmol/ml) were observed immediately after exercise at 36% MLP. Significant increases in plasma epinephrine were observed immediately after exercise at 36% MLP (i.e., from mean resting value of 2.22 to 3.11 pmol/ml) and 55% MLP (i.e., from mean resting value of 1.67 to 2.98 pmol/ml) and 15 min after exercise at 100% MLP (i.e., from mean resting value of 1.92 to 3.88 pmol/ml). Significant increases for plasma norepinephrine were observed immediately after exercise (36, 55, 73, and 100% MLP), 5 min after exercise (36, 55, and 73% MLP), and 15 min after exercise (36% MLP). Increases in whole blood lactate were observed at all points after exercise for 36, 55, and 73% MLP and 5 min after exercise for 100% MLP. These data show that brief high-intensity exercise results in differential response patterns of catecholamines and proenkephalin peptide F immunoreactivity.
在9名健康男性中，使用计算机化的自行车测力计，在四种强度[最大腿部力量（MLP）的36%、55%、73%和100%]下进行最大运动至力竭前后的不同日子，检测血浆前脑啡肽原肽F免疫反应性和儿茶酚胺。36%、55%、73%和100% MLP的平均持续时间分别为3.31、0.781、0.270和0.1分钟。所有强度均高于个体受试者引发峰值摄氧量的强度。在运动前、运动后即刻以及运动后5分钟和15分钟采集血样。在36% MLP运动后即刻观察到血浆肽F免疫反应性显著（P<0.05）增加（即从平均静息值0.18增加到0.43 pmol/ml）。在36% MLP运动后即刻（即从平均静息值2.22增加到3.11 pmol/ml）、55% MLP运动后即刻（即从平均静息值1.67增加到2.98 pmol/ml）以及100% MLP运动后15分钟（即从平均静息值1.92增加到3.88 pmol/ml）观察到血浆肾上腺素显著增加。在运动后即刻（36%、55%、73%和100% MLP）、运动后5分钟（36%、55%和73% MLP）以及运动后15分钟（36% MLP）观察到血浆去甲肾上腺素显著增加。在36%、55%和73% MLP运动后的所有时间点以及100% MLP运动后5分钟观察到全血乳酸增加。这些数据表明，短暂的高强度运动导致儿茶酚胺和前脑啡肽原肽F免疫反应性的不同反应模式。
