Cardiovascular Institute Middelheim, AZ Middelheim, Antwerp, Belgium.
Cardiol J. 2010;17(1):92-5.
Spontaneous coronary artery dissection (SCAD) is a rare cause of acute coronary syndrome and sudden cardiac death. It should be suspected in every healthy young woman without cardiac risk factors, especially during the peripartum or postpartum periods. It is important to check for a history of drug abuse, collagen vascular disease or blunt trauma of the chest. Coronary angiography is essential for diagnosis and early management. We wonder whether thrombolysis might aggravate coronary dissection. All types of treatment (medical therapy, percutaneous intervention or surgery) improve the prognosis without affecting survival times if used appropriately according to the clinical stability and the angiographic features of the involved coronary arteries. Prompt recognition and targeted treatment improve outcomes. We report a case of SCAD in a young female free of traditional cardiovascular risk factors, who presented six hours after thrombolysis for ST elevation myocardial infarction. Coronary angiography showed a dissection of the left anterior descending and immediate branch. She had successful coronary artery bypass grafting, with complete healing of left anterior descending dissection.
自发性冠状动脉夹层 (SCAD) 是急性冠状动脉综合征和心源性猝死的罕见病因。对于没有心脏危险因素的每个健康年轻女性,尤其是在围产期或产后期间,都应怀疑该病。重要的是要检查药物滥用、胶原血管疾病或胸部钝性创伤的病史。冠状动脉造影对于诊断和早期治疗至关重要。我们想知道溶栓是否会加重冠状动脉夹层。如果根据受累冠状动脉的临床稳定性和血管造影特征进行适当治疗,所有类型的治疗(药物治疗、经皮介入或手术)都可以改善预后,而不会影响生存时间。及时识别和针对性治疗可改善预后。我们报告了一例年轻女性无传统心血管危险因素的 SCAD 病例,该患者在 ST 段抬高型心肌梗死溶栓治疗后 6 小时出现。冠状动脉造影显示左前降支和即刻分支夹层。她成功进行了冠状动脉旁路移植术,左前降支夹层完全愈合。