Cardiology Division, Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
Korean Circ J. 2013 Jul;43(7):491-6. doi: 10.4070/kcj.2013.43.7.491. Epub 2013 Jul 31.
Spontaneous coronary artery dissection (SCAD) is a rare and occasionally life-threatening cause of acute coronary syndrome. Patients may present with clinical scenarios ranging from angina pectoris to cardiogenic shock to sudden cardiac death, and it may be a potentially life-threatening condition if not recognized. However, its etiology, pathophysiology and optimal therapeutic strategies have not been well understood. SCAD is diagnosed on the basis of coronary angiography, but complementary techniques as such intravascular ultrasound (IVUS) and optical coherence tomography should be considered for diagnostic clarification where appropriate. Likewise, the selection of treatment strategy depends upon the clinical manifestation, location and the extent of dissection and amount of ischemic myocardium at risk. Herein, we present the case of a 35-year-old woman who presented with acute myocardial infarction. She was diagnosed by IVUS with spontaneous diffuse dissection of the left anterior descending artery without atheroma, treated with percutaneous coronary stenting, and had a favorable clinical course and was discharged on medical therapy.
自发性冠状动脉夹层 (SCAD) 是一种罕见且偶尔危及生命的急性冠状动脉综合征的病因。患者的临床表现从心绞痛到心源性休克到心搏骤停不等,如果不能得到及时识别,可能会危及生命。然而,其病因、病理生理学和最佳治疗策略尚未得到充分理解。SCAD 的诊断基于冠状动脉造影,但在适当的情况下,应考虑使用血管内超声 (IVUS) 和光学相干断层扫描等补充技术来明确诊断。同样,治疗策略的选择取决于临床表现、夹层的位置和程度以及有缺血风险的心肌量。在此,我们报告了一位 35 岁女性的病例,她因急性心肌梗死就诊。IVUS 诊断为左前降支自发性弥漫性夹层,无动脉粥样硬化,采用经皮冠状动脉支架置入术治疗,临床转归良好,出院后继续药物治疗。