STELA Dairy Research Center, Nutraceuticals and Functional Foods Institute, Université Laval, G1K 7P4 Québec, QC, Canada.
BMC Microbiol. 2010 Jan 27;10:22. doi: 10.1186/1471-2180-10-22.
BACTIBASE is an integrated open-access database designed for the characterization of bacterial antimicrobial peptides, commonly known as bacteriocins.
For its second release, BACTIBASE has been expanded and equipped with additional functions aimed at both casual and power users. The number of entries has been increased by 44% and includes data collected from published literature as well as high-throughput datasets. The database provides a manually curated annotation of bacteriocin sequences. Improvements brought to BACTIBASE include incorporation of various tools for bacteriocin analysis, such as homology search, multiple sequence alignments, Hidden Markov Models, molecular modelling and retrieval through our taxonomy Browser.
The provided features should make BACTIBASE a useful tool in food preservation or food safety applications and could have implications for the development of new drugs for medical use. BACTIBASE is available at http://bactibase.pfba-lab-tun.org.
BACTIBASE 是一个集成的开放访问数据库，旨在对细菌抗菌肽（通常称为细菌素）进行特征描述。
在其第二个版本中，BACTIBASE 进行了扩展，并配备了针对普通用户和高级用户的其他功能。条目数量增加了 44%，其中包括从已发表文献和高通量数据集收集的数据。该数据库提供了细菌素序列的人工注释。BACTIBASE 的改进包括纳入了各种细菌素分析工具，如同源搜索、多序列比对、隐马尔可夫模型、分子建模以及通过我们的分类浏览检索。
提供的功能应该使 BACTIBASE 成为食品保鲜或食品安全应用的有用工具，并可能对开发用于医疗用途的新药产生影响。BACTIBASE 可在 http://bactibase.pfba-lab-tun.org 上获取。
