氮氧自由基作为双极化子促进 1,3-偶极环加成与环辛炔的快速应变。
Nitrones as dipoles for rapid strain-promoted 1,3-dipolar cycloadditions with cyclooctynes.
机构信息
Steacie Institute for Molecular Sciences, National Research Council of Canada, 100 Sussex Drive, Ottawa, ON, CanadaK1A 0R6.
出版信息
Chem Commun (Camb). 2010 Feb 14;46(6):931-3. doi: 10.1039/b921630h. Epub 2009 Dec 23.
DOI:10.1039/b921630h
PMID:20107654
Abstract
Strain-promoted cycloadditions of nitrones with cyclooctynes (k(2) = 1.5 M(-1) s(-1) at 25 degrees C) are up to 25 times more rapid than comparable reactions of azides.
摘要
氮氧自由基与环辛炔的应变促进环加成反应（在 25°C 下，k(2) = 1.5 M(-1) s(-1)）比类似的叠氮化物反应快 25 倍。
Zotero 插件