Service de Dermatologie, Université Paul Sabatier-Toulouse III et CHU Toulouse, Toulouse, France.
Acta Derm Venereol. 2010;90(1):12-7. doi: 10.2340/00015555-0789.
Pruritus has a well-known association with Hodgkin's disease and other nodal lymphomas; indeed it often reveals the disease. Pruritus is also an important symptom of cutaneous T-cell lymphomas. Lymphoma-associated itch is thus both frequent and severe, but its pathophysiology remains unclear. Few studies have evaluated the efficacy of therapeutic agents in the management of cutaneous T-cell lymphoma-related pruritus. The main objective of treatment remains disease control. Pruritus management is generally based on the physician's experience. Treatment is very difficult, especially in Sézary syndrome. We present here management strategies for cutaneous lymphoma-associated pruritus.
瘙痒与霍奇金病和其他结外淋巴瘤有明确的关联；事实上，它常常提示疾病的发生。瘙痒也是皮肤 T 细胞淋巴瘤的一个重要症状。因此，淋巴瘤相关性瘙痒不仅频繁而且严重，但它的病理生理学仍不清楚。很少有研究评估治疗药物在治疗皮肤 T 细胞淋巴瘤相关性瘙痒中的疗效。治疗的主要目标仍然是控制疾病。瘙痒的管理通常基于医生的经验。治疗非常困难，尤其是在蕈样肉芽肿病中。我们在此介绍皮肤淋巴瘤相关性瘙痒的管理策略。
