Faculty of Pharmacy, Meijo University, Yagoto, Tempaku-ku, Nagoya, Japan.
Planta Med. 2010 Jun;76(9):916-9. doi: 10.1055/s-0029-1240849. Epub 2010 Jan 27.
Two new compounds, erybacin A (1) and erybacin B (2), together with 10 known compounds (3- 12), were isolated from the roots of Erythrina herbacea. Their structures were established on the basis of spectroscopic analyses. Erybacin A is a rare, naturally occurring 1-hydroxy-1,3-diphenylpropan-2-one derivative. The isolated compounds were evaluated for their antibacterial activity against 13 strains of methicillin-resistant Staphylococcus aureus (MRSA). The new compound 2 showed a potent bactericidal activity against MRSA.
从含羞草的根部分离得到了两种新化合物，erybacin A（1）和 erybacin B（2），以及 10 种已知化合物（3-12）。它们的结构是基于光谱分析确定的。Erybacin A 是一种罕见的天然 1-羟基-1,3-二苯基-2-丙酮衍生物。对分离得到的化合物进行了抗 13 株耐甲氧西林金黄色葡萄球菌（MRSA）的抗菌活性评价。新化合物 2 对 MRSA 具有很强的杀菌活性。
