Tanaka Hitoshi, Atsumi Ikunori, Hasegawa Motori, Hirata Miyuki, Sakai Tatsuko, Sato Masaru, Yamaguchi Ryozo, Tateishi Yoichi, Tanaka Toshiyuki, Fukai Toshio
Nat Prod Commun. 2015 Mar;10(3):499-501.
Two new isoflavanones, eryvarins Y (1) and Z (2), together with three known compounds (3-5) were isolated from the roots of Erythrina variegata. The structures of 1 and.2 were established on the basis of spectroscopic data. The new compounds are peculiar isoflavanones, possessing both a 3-methylbut-2-en- 1-yl group and a 2-hydroxy-3-methylbut-3-en-1-yl group. Among the isolates, orientanol E (5) exhibited potent antibacterial activity against methicillin- resistant Staphylococcus aureus (MRSA) strains.
从刺桐的根部分离出两种新的异黄酮，刺桐黄素Y（1）和Z（2），以及三种已知化合物（3 - 5）。1和2的结构通过光谱数据确定。新化合物是特殊的异黄酮，同时具有一个3 - 甲基丁 - 2 - 烯 - 1 - 基和一个2 - 羟基 - 3 - 甲基丁 - 3 - 烯 - 1 - 基。在分离出的化合物中，orientanol E（5）对耐甲氧西林金黄色葡萄球菌（MRSA）菌株表现出强效抗菌活性。
