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定植清除后万古霉素耐药粪肠球菌直肠再定植和再获得。

Relapse and reacquisition of rectal colonization by vancomycin-resistant Enterococcus faecium after decolonization.

机构信息

Department of Laboratory Medicine, Ajou University School of Medicine, Youngtong-Gu, Suwon, Korea.

出版信息

Epidemiol Infect. 2010 Oct;138(10):1449-53. doi: 10.1017/S0950268810000038. Epub 2010 Jan 29.

DOI:10.1017/S0950268810000038
PMID:20109265
Abstract

To better understand the epidemiology of colonization of vancomycin-resistant enterococci (VRE), we performed an 8-year retrospective study of all hospitalized patients with recurrent VRE colonization after they were documented as being clear of VRE and compared the primary colonization isolates and recolonization isolates by pulsed-field gel electrophoresis and Tn1546 typing. Review of the medical records of all patients showed that of the 15 patients with recurrent colonization, six continued to be hospitalized on the same floor. Five were discharged home and then readmitted. Four were moved to another floor. Patients who remained on the same floor were recolonized with a strain that was indistinguishable from the original colonizing strain. Patients who were moved or were discharged had de novo VRE colonization with strains distinct from the original colonizing strain.

摘要

为了更好地了解耐万古霉素肠球菌(VRE)定植的流行病学,我们对所有记录明确无 VRE 定植后再次发生 VRE 定植的住院患者进行了 8 年的回顾性研究,并通过脉冲场凝胶电泳和 Tn1546 分型比较了原发性定植分离株和再定植分离株。对所有患者的病历进行回顾显示,在 15 例再次定植的患者中,有 6 例继续在同一病房住院。5 例出院后再次入院。4 例被转至其他楼层。仍在同一病房的患者被与原始定植株无法区分的菌株再定植。转至其他病房或出院的患者发生了与原始定植株不同的新的 VRE 定植。

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