[硬化性苔藓]
[Lichen sclerosus].
作者信息
Monsálvez V, Rivera R, Vanaclocha F
机构信息
Servicio de Dermatología, Hospital 12 de Octubre, Madrid, España.
出版信息
Actas Dermosifiliogr. 2010 Jan-Feb;101(1):31-8.
PMID:20109390
Abstract
Lichen sclerosus is a chronic inflammatory mucocutaneous disease that is highly bothersome for men and women of all ages. The exact etiology is unknown, although genetic and autoimmune factors, as well as infections, have been implicated in its pathogenesis. First-line treatment is highly potent topical corticosteroid therapy for short periods. Surgery is reserved for cases of phimosis, urethral stenosis, synechiae, and squamous cell carcinoma.
摘要
硬化性苔藓是一种慢性炎症性黏膜皮肤疾病，对各年龄段的男性和女性都造成极大困扰。尽管遗传、自身免疫因素以及感染都被认为与该病的发病机制有关，但其确切病因尚不清楚。一线治疗是短期使用高效外用皮质类固醇疗法。手术仅适用于包茎、尿道狭窄、粘连以及鳞状细胞癌的病例。
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