Department of Chemistry, University of Nebraska-Lincoln, NE 68588, USA.
Nat Prod Rep. 2010 Feb;27(2):255-78. doi: 10.1039/b912037h. Epub 2009 Dec 4.
This review covers the recent literature on the release mechanisms for polyketides and nonribosomal peptides produced by microorganisms. The emphasis is on the novel enzymology and mechanistic insights revealed by the biosynthetic studies of new natural products.
这篇综述涵盖了微生物产生的聚酮类化合物和非核糖体肽的释放机制的最新文献。重点是新天然产物生物合成研究揭示的新颖的酶学和机制见解。