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1995-2004 年德国与奥地利髋部骨折发病率及趋势比较:一项流行病学研究。

Comparison of hip fracture incidence and trends between Germany and Austria 1995-2004: an epidemiological study.

机构信息

Faculty of Public Health, Department of Epidemiology and International Public Health, School of Public Health, Bielefeld University, Bielefeld, Germany.

出版信息

BMC Public Health. 2010 Jan 29;10:46. doi: 10.1186/1471-2458-10-46.

Abstract

BACKGROUND

Several studies evaluated variations in hip fracture incidences, as well as trends of the hip fracture incidences. Comparisons of trends are lacking so far. We compared the incidence rates and, in particular, its trends between Austria and Germany 1995 to 2004 analysing national hospital discharge diagnosis register data.

METHODS

Annual frequencies of hip fractures and corresponding incidences per 100,000 person years were estimated, overall and stratified for sex and age, assuming Poisson distribution. Multiple Poisson regression models including country and calendar year, age and sex were used to analyse differences in incidence and trend. The difference of annual changes between the two countries was explored using an interaction term (calender year * country).

RESULTS

Overall, the increase of hip fracture risk was 1.31 fold higher (95% CI 1.29-1.34) in Austria compared to Germany, adjusted for age, sex, and calendar year. The risk increase was comparable for both sexes (males: RR 1.35 (1.32-1.37), females: RR 1.31 (1.29-1.33)). Hip fracture trend from 1995 to 2004 indicates an increase in both countries without a statistically significant difference between Austria and Germany (interaction term: p = 0.67).

CONCLUSION

In this study comparing hip fracture incidences and its trend using pooled data, the incidence in Austria was 30% higher compared to its neighbouring country Germany. For both countries a similar increasing trend of hip fracture incidence over the 10-year study period was calculated. The results need confirmation by other studies.

摘要

背景

多项研究评估了髋部骨折发生率的变化以及髋部骨折发生率的趋势。目前还缺乏对这些趋势的比较。我们通过分析国家医院出院诊断登记数据,比较了 1995 年至 2004 年奥地利和德国的发生率,并特别比较了其趋势。

方法

假设泊松分布,计算了髋部骨折的年频率以及每 10 万人年的相应发生率,同时按性别和年龄分层。使用包含国家和日历年份、年龄和性别的多泊松回归模型来分析发病率和趋势的差异。通过交互项(日历年份*国家)探索两国之间年度变化的差异。

结果

总体而言,与德国相比,奥地利髋部骨折风险的增加幅度高 1.31 倍(95%CI1.29-1.34),调整了年龄、性别和日历年份。两种性别之间的风险增加相似(男性:RR1.35(1.32-1.37),女性:RR1.31(1.29-1.33))。1995 年至 2004 年的髋部骨折趋势表明,两国都呈上升趋势,但奥地利和德国之间没有统计学上的显著差异(交互项:p=0.67)。

结论

在这项使用汇总数据比较髋部骨折发生率及其趋势的研究中,与邻国德国相比,奥地利的发生率高出 30%。对于这两个国家,在 10 年的研究期间,髋部骨折发生率都呈上升趋势。这些结果需要其他研究加以证实。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f3e2/2831031/1504c9919f20/1471-2458-10-46-1.jpg

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