Department of Physiological Nursing and Institute for Human Genetics, University of California, San Francisco, USA.
J Assoc Nurses AIDS Care. 2010 Mar-Apr;21(2):125-33. doi: 10.1016/j.jana.2009.10.003. Epub 2010 Jan 29.
Studies suggest that people living with HIV (PLWH) experience many unrelieved symptoms. The purpose of this study was to estimate the occurrence of pain in adult PLWH and to determine whether participants with pain differed from those without pain on selected demographic factors, clinical characteristics, symptoms of fatigue, sleep disturbance, anxiety, or depression. The authors conducted a descriptive, comparative, and correlational study of 317 PLWH seen at academic and community clinics in San Francisco. Participants completed a demographic questionnaire, the Memorial Symptom Assessment Scale, the Fatigue Severity Scale, the General Sleep Disturbance Scale, the Profile of Moods State Tension-Anxiety subscale, and the Center for Epidemiological Studies-Depression Scale. Clinical characteristics (i.e., disease and treatment information) were obtained by self-report. A single item on pain from the Memorial Symptom Assessment Scale was used to classify participants into those with and without pain. Pain was highly prevalent (55%) and was associated with immune status (CD4+ T-cell count), race, and sleep disturbance, but not with age, gender, or symptoms of fatigue, depression, or anxiety.
研究表明，HIV 感染者（PLWH）经历许多未缓解的症状。本研究的目的是估计成人 PLWH 中疼痛的发生情况，并确定有疼痛的参与者与无疼痛的参与者在选定的人口统计学因素、临床特征、疲劳症状、睡眠障碍、焦虑或抑郁方面是否存在差异。作者对旧金山学术和社区诊所的 317 名 PLWH 进行了描述性、比较性和相关性研究。参与者完成了人口统计学问卷、纪念症状评估量表、疲劳严重程度量表、一般睡眠障碍量表、情绪状态紧张焦虑分量表和流行病学研究中心抑郁量表。临床特征（即疾病和治疗信息）通过自我报告获得。纪念症状评估量表上的一个关于疼痛的单项问题用于将参与者分为有疼痛和无疼痛的组。疼痛的发生率很高（55%），与免疫状态（CD4+T 细胞计数）、种族和睡眠障碍有关，但与年龄、性别或疲劳、抑郁或焦虑症状无关。
