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用于炎症性肠病的无线胶囊

Wireless capsule in inflammatory bowel disease.

作者信息

Flamant M, Trang C, Bourreille A

机构信息

Institut des Maladies de l'Appareil Digestif, CHU Hôtel-Dieu, Nantes, France.

出版信息

Gastroenterol Clin Biol. 2009 Jun;33 Suppl 3:S183-9. doi: 10.1016/S0399-8320(09)73153-7.

DOI:10.1016/S0399-8320(09)73153-7
PMID:20117341
Abstract

Capsule endoscopy (CE) is a safe, non-invasive diagnostic tool to evaluate small bowel lesions. CE, like conventional endoscopy, can detect focal and small-ulcerated lesions along the entire length of the small bowel, which are not identified by other imaging techniques. Meta-analysis has shown that CE is better than any other radiological technique to detect small bowel lesions in patients with suspected or known Crohn's disease (CD). In unclassified colitis, CE is also useful in distinguishing CD and ulcerative colitis (UC). In established CD, CE may be used to detect post-operative recurrence, determine the extent of small bowel lesions and link ulcerated lesions with clinical symptoms. Although CE is well tolerated there is a theoretical risk of capsule impaction in general and in CD in particular. To avoid capsule impaction, a new option called the "patency capsule" is available especially in patients with symptoms suggesting small bowel obstruction. However, few data are available about this new device and its use in clinical practice needs to be clarified.

摘要

胶囊内镜检查(CE)是一种用于评估小肠病变的安全、无创诊断工具。与传统内镜检查一样,CE可以检测出小肠全长的局灶性和小溃疡病变,而其他成像技术无法识别这些病变。荟萃分析表明,在疑似或已知克罗恩病(CD)的患者中,CE在检测小肠病变方面优于任何其他放射学技术。在未分类的结肠炎中,CE也有助于区分CD和溃疡性结肠炎(UC)。在确诊的CD中,CE可用于检测术后复发、确定小肠病变范围以及将溃疡病变与临床症状联系起来。尽管CE耐受性良好,但一般情况下尤其是在CD中存在胶囊嵌顿的理论风险。为避免胶囊嵌顿,有一种名为“通畅胶囊”的新选择,尤其适用于有小肠梗阻症状的患者。然而,关于这种新设备的数据很少,其在临床实践中的应用需要进一步明确。

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