癌症患者及其家庭成员的流感疫苗接种。

Influenza vaccination among individuals with cancer and their family members.

机构信息

Department of Biostatistics, M. D. Anderson Cancer Center, University of Texas, Houston, 77230-1402, USA.

出版信息

Am J Prev Med. 2010 Jan;38(1):61-9. doi: 10.1016/j.amepre.2009.09.032.

DOI:10.1016/j.amepre.2009.09.032

PMID:20117558

Abstract

BACKGROUND

Influenza vaccination for family members of patients with cancer lowers patients' risk of influenza and related complications.

PURPOSE

This study aims to examine the utilization of influenza vaccination among such families.

METHODS

Individuals directly or indirectly affected by cancer and a cancer-free control group were identified from the 2005 and 2006 Medical Expenditure Panel Survey: current patients (CURR-I) and their family members (CURR-F); previous patients (PREV-I) and family members (PREV-F); and individuals in families not affected by cancer (I-F). Logistic regressions with appropriate weighting algorithms for survey data were performed to compare utilization among these five groups, while controlling for confounding factors (e.g., demographics, SES).

RESULTS

The proportion of those vaccinated was substantially higher among patients with cancer. It was 58.7%, 54.7%, 43.83%, 39.73%, and 29.3% for CURR-I, PREV-I, CURR-F, PREV-F, and I-F, respectively. A similar pattern was observed in analyses stratified by age groups (18-49, 50-64, and > or =65 years). Results from logistic regressions indicated that the CURR-I group was significantly more likely to have influenza vaccine than I-F (OR [CI]=1.62 [1.10, 2.36]; 1.50 [1.11, 2.02]; and 1.42 [1.06, 1.92] for those aged 18-49, 50-64, and > or =65 years, respectively), but the differences between family members of patients with cancer and the control were not significant after controlling for the confounders. A significant difference between PREV-I and I-F was observed for only those aged > or =65 years (OR [CI]=1.47 [1.09, 1.99]).

CONCLUSIONS

Influenza vaccination was underutilized (<45%) among family members of patients with cancer. To reduce health risks for cancer survivors, prevention efforts should be extended to their family members.

摘要

背景

为癌症患者的家庭成员接种流感疫苗可降低患者患流感和相关并发症的风险。

目的

本研究旨在调查此类家庭中流感疫苗的接种情况。

方法

从 2005 年和 2006 年的医疗支出调查中确定了直接或间接受癌症影响的个体以及无癌症对照个体：当前患者（CURR-I）及其家庭成员（CURR-F）；既往患者（PREV-I）及其家庭成员（PREV-F）；以及未受癌症影响的家庭中的个体（I-F）。对这些五组数据进行了带有适当加权算法的逻辑回归，以在控制混杂因素（例如，人口统计学，SES）的情况下比较利用率。

结果

癌症患者中接种疫苗的比例大大提高。CURR-I、PREV-I、CURR-F、PREV-F 和 I-F 的疫苗接种率分别为 58.7%、54.7%、43.83%、39.73%和 29.3%。在按年龄组（18-49 岁、50-64 岁和≥65 岁）进行分层的分析中也观察到了类似的模式。逻辑回归的结果表明，CURR-I 组接种流感疫苗的可能性明显高于 I-F（OR[CI]为 1.62[1.10，2.36]；1.50[1.11，2.02]；1.42[1.06，1.92]，年龄在 18-49 岁、50-64 岁和≥65 岁的人），但在控制混杂因素后，癌症患者的家庭成员与对照组之间的差异并不显著。仅在年龄≥65 岁的人群中观察到 PREV-I 和 I-F 之间存在显著差异（OR[CI]为 1.47[1.09，1.99]）。