Northwestern University, Feinberg School of Medicine, Chicago, IL, USA.
Vasc Med. 2010 Apr;15(2):83-90. doi: 10.1177/1358863X09353653. Epub 2010 Jan 29.
Among 355 peripheral arterial disease (PAD) patients with low density lipoprotein cholesterol (LDL-C) levels > or = 70 mg/dl, we assessed knowledge regarding optimal LDL levels and the importance of LDL-C-lowering therapy. We also assessed PAD participants' behaviors and attitudes regarding their engagement with their physician in treatment decisions for LDL-C lowering. The average baseline LDL-C level of participants was 103.4 mg/dl +/- 30.7 mg/dl. Seventy-six percent of participants were taking at least one cholesterol-lowering medication. Sixty-six percent were unable to define their optimal LDL-C. Only 47% strongly agreed that their own actions and decisions could reduce their LDL-C. Just 29.8% were aware that patients who request specific medications from their physician were more likely to receive them, and 16% had asked their physician whether they should be taking more cholesterol-lowering medication. These findings suggest that further study is needed to identify effective interventions to educate PAD patients and their physicians about the importance of cholesterol-lowering therapy and to encourage PAD patients to participate with their physician in decisions regarding cholesterol-lowering treatment. Clinical Trial Registration - URL: http://www.clinicaltrials.gov. Unique identifier: NCT00217919.
在 355 名低密度脂蛋白胆固醇(LDL-C)水平>或= 70mg/dl 的外周动脉疾病(PAD)患者中,我们评估了他们对最佳 LDL 水平以及 LDL-C 降低治疗重要性的了解。我们还评估了 PAD 参与者在与医生共同参与 LDL-C 降低治疗决策方面的行为和态度。参与者的平均基线 LDL-C 水平为 103.4mg/dl +/- 30.7mg/dl。76%的参与者至少服用一种降胆固醇药物。66%的人无法定义自己的最佳 LDL-C。只有 47%的人强烈认为自己的行为和决定可以降低 LDL-C。只有 29.8%的人知道患者向医生要求特定药物时更有可能获得这些药物,而 16%的人曾询问过医生是否应该服用更多的降胆固醇药物。这些发现表明,需要进一步研究以确定有效的干预措施,向 PAD 患者及其医生传授降胆固醇治疗的重要性,并鼓励 PAD 患者参与与医生共同决定降胆固醇治疗。临床试验注册-网址:http://www.clinicaltrials.gov。独特标识符:NCT00217919。