Department of Pathology and Infectious Diseases, The Royal Veterinary College, Hertfordshire, UK.
Vet Pathol. 2010 Mar;47(2):343-5. doi: 10.1177/0300985809358429. Epub 2009 Dec 31.
Congenital vascular tumors of the skin have been described in people and a few animals, but unlike infantile hemangiomas in children, spontaneous regression has not been described in animals. A 2-day-old male Belgian Blue cross calf was presented for multiple congenital cutaneous masses that were soft, alopecic, and hyperemic; the calf had no other apparent abnormalities. Two weeks later, one mass had regressed. Surgical excision of one of the remaining masses was performed; histopathologic and immunohistochemical findings were considered diagnostic for epithelioid hemangioma. Eight months following initial presentation, all the masses had regressed spontaneously. This constitutes the first account in the veterinary literature of spontaneous regression in a congenital vascular tumor.
先天性皮肤血管肿瘤在人和少数动物中已有描述,但与儿童的婴幼儿血管瘤不同,在动物中尚未描述自发性消退。一只 2 天大的雄性比荷卢杂交牛犊因多发性先天性皮肤肿块就诊,这些肿块质地柔软、无毛且充血;牛犊没有其他明显的异常。2 周后,一个肿块已消退。对其中一个剩余肿块进行了手术切除;组织病理学和免疫组织化学检查结果被认为是上皮样血管瘤的诊断依据。初次就诊 8 个月后,所有肿块均自发消退。这是兽医文献中首例先天性血管肿瘤自发性消退的报道。