从桑叶中提取的四种新型2-芳基苯并呋喃衍生物
Four new 2-arylbenzofuran derivatives from leaves of Morus alba L.
作者信息
Yang Yan, Gong Ting, Liu Chao, Chen Ruo-Yun
机构信息
Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education & Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College.
出版信息
Chem Pharm Bull (Tokyo). 2010 Feb;58(2):257-60. doi: 10.1248/cpb.58.257.
Four new 2-arylbenzofuran derivatives, moracins V-Y (1-4), together with two known compounds, moracin N (5) and moracin P (6), were isolated from the leaves of Morus alba L. Their structures were elucidated by spectroscopic analysis. Moracins X (3) and Y (4) represent unusual substituted group compared with 2-arylbenzofuran derivatives, which were isolated from the genus Morus. Compounds 2-5 were evaluated for cytotoxicity against several human cancer cell lines.
从桑叶中分离出四种新的2-芳基苯并呋喃衍生物，桑色素V - Y（1 - 4），以及两种已知化合物，桑色素N（5）和桑色素P（6）。通过光谱分析阐明了它们的结构。与从桑属植物中分离出的2-芳基苯并呋喃衍生物相比，桑色素X（3）和Y（4）具有不同寻常的取代基。对化合物2 - 5进行了针对几种人类癌细胞系的细胞毒性评估。
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