Yi Chae S, Lee Do W
Department of Chemistry, Marquette University, Milwaukee, Wisconsin 53201-1881.
Organometallics. 2009 Jan 29;28(4):947-949. doi: 10.1021/om8010883.
The tetranuclear ruthenium-mu-oxo-mu-hydroxo-hydride complex {(PCy(3))(CO)RuH(mu(4)-O)(mu(3)-OH)(mu(2)-OH)} (1) was found to be a highly effective catalyst for the transfer dehydrogenation of amines and carbonyl compounds. For example, the initial turnover rate of the dehydrogenation of 2-methylindoline was measured to be 1.9 s(-1) with the TON of 7950 after 1 h at 200 degrees C. The extensive H/D scrambling patterns observed from the dehydrogenation reaction of indoline-N-d(1) and indoline-alpha-d(2) suggest a monohydride mechanistic pathway with the C-H bond activation rate-limiting step.
四核钌-μ-氧-μ-羟基-氢化物配合物{(PCy(3))(CO)RuH(μ(4)-O)(μ(3)-OH)(μ(2)-OH)} (1)被发现是胺类和羰基化合物转移脱氢反应的高效催化剂。例如，2-甲基二氢吲哚脱氢反应的初始周转速率在200℃下1小时后测得为1.9 s(-1)，TON为7950。从吲哚-N-d(1)和吲哚-α-d(2)的脱氢反应中观察到的广泛的H/D交换模式表明，其机理途径为单氢化物，其中C-H键活化是速率限制步骤。
