Department of Hospital Pathology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
J Korean Med Sci. 2010 Feb;25(2):220-5. doi: 10.3346/jkms.2010.25.2.220. Epub 2010 Jan 19.
For intraoperative consultation of mucinous adenocarcinoma involving the ovary, it would be useful to have approaching methods in addition to the traditional limited microscopic findings in order to determine the nature of the tumors. Mucinous adenocarcinomas involving the ovaries were evaluated in 91 cases of metastatic mucinous adenocarcinomas and 19 cases of primary mucinous adenocarcinomas using both an original algorithm (unilateral >or=10 cm tumors were considered primary and unilateral <10 cm tumors or bilateral tumors were considered metastatic) and a modified cut-off size algorithm. With 10 cm, 13 cm, and 15 cm size cut-offs, the algorithm correctly classified primary and metastatic tumors in 82.7%, 87.3%, and 89.1% of cases and in 80.6%, 84.9%, and 87.1% of signet ring cell carcinoma (SRC) excluded cases. In total cases and SRC excluded cases, 98.0% and 97.2% of bilateral tumors were metastatic and 100% and 100% of unilateral tumors <10 cm were metastatic, respectively. In total cases and SRC excluded cases, 68.4% and 68.4% of unilateral tumors >or=15 cm were primary, respectively. The diagnostic algorithm using size and laterality, in addition to clinical history, preoperative image findings, and operative findings, is a useful adjunct tool for differentiation of metastatic mucinous adenocarcinomas from primary mucinous adenocarcinomas of the ovary.
对于涉及卵巢的黏液性腺癌的术中咨询，除了传统的有限显微镜发现之外，还需要有一些接近方法，以便确定肿瘤的性质。对 91 例转移性黏液性腺癌和 19 例原发性黏液性腺癌进行了评估，使用了原始算法（单侧> = 10 cm 的肿瘤被认为是原发性的，单侧< 10 cm 的肿瘤或双侧肿瘤被认为是转移性的）和改良的截止尺寸算法。在使用 10 cm、13 cm 和 15 cm 大小截止值时，该算法在 82.7%、87.3%和 89.1%的病例中正确分类了原发性和转移性肿瘤，在 80.6%、84.9%和 87.1%的排除印戒细胞癌（SRC）病例中正确分类。在所有病例和排除 SRC 的病例中，98.0%和 97.2%的双侧肿瘤均为转移性，100%和 100%的单侧< 10 cm 的肿瘤均为转移性。在所有病例和排除 SRC 的病例中，分别有 68.4%和 68.4%的单侧肿瘤> = 15 cm 为原发性。除了临床病史、术前影像学发现和手术发现外，使用大小和侧位以及组织学检查的诊断算法是区分卵巢转移性黏液性腺癌和原发性黏液性腺癌的有用辅助工具。
