Department of Internal Medicine, Hallym University Sacred Heart Hospital, Anyang, Korea.
J Korean Med Sci. 2010 Feb;25(2):293-8. doi: 10.3346/jkms.2010.25.2.293. Epub 2010 Jan 22.
The purpose of this study was to estimate the prevalence of radiographic and symptomatic knee osteoarthritis (OA) among community residents and to elucidate the relevant risk factors. This prospective, population-based study was conducted on residents over 50 yr of age in Chuncheon. Subjects completed an interview based on a standardized questionnaire and clinical evaluation including standardized weight bearing semiflexed knee A-P radiographs. We defined a subject with the Kellgren and Lawrence grade >or=2 as having radiographic knee OA (ROA). Symptomatic knee OA (SOA) was defined by the presence of both ROA and knee pain. We obtained symptom information and radiographs from 504 subjects. The prevalence of ROA and SOA was 37.3% and 24.2%, respectively. The prevalence of both ROA and SOA was significantly higher among women than among men. Multivariate analysis revealed that the presence of hypertension, and a manual occupation were significantly associated with the presence of ROA and SOA. Lower level of education was significantly associated with the presence of ROA, and female sex with the presence of SOA. In conclusion, both ROA and SOA are common in the aged adult population of Korea, with preponderance for women.
本研究旨在评估社区居民影像学和症状性膝骨关节炎(OA)的患病率,并阐明相关的危险因素。这是一项在春川市进行的、针对 50 岁以上人群的前瞻性、基于人群的研究。受试者完成了一份基于标准化问卷的访谈和临床评估,包括标准化负重半屈位膝关节前后位 X 线片。我们将 Kellgren 和 Lawrence 分级≥2 的患者定义为存在影像学膝 OA(ROA)。症状性膝 OA(SOA)定义为 ROA 合并膝关节疼痛。我们从 504 名受试者中获得了症状信息和 X 线片。ROA 和 SOA 的患病率分别为 37.3%和 24.2%。ROA 和 SOA 的患病率在女性中明显高于男性。多变量分析显示,高血压和体力劳动职业与 ROA 和 SOA 的存在显著相关。较低的教育水平与 ROA 的存在显著相关,而女性与 SOA 的存在显著相关。总之,韩国老年人群中 ROA 和 SOA 都很常见,女性更为多见。