Piyakunmala Kriangsak, Sangkomkamhang Thananit, Chareonchonvanitch Keerati
Department of Orthopaedics, Khon Kaen Hospital, Khon Kaen 40000, Thailand.
J Med Assoc Thai. 2009 Dec;92 Suppl 6:S147-51.
To examine the incidence rate and extension of non-traumatic asymptomatic osteonecrosis of the contralateral femoral head (ONFH) in high-risk patient groups.
A cross-sectional design was used. We studied patients who visited at Orthopedics department, Khon Kaen hospital between January 2007 and December 2008. Only high-risk patients diagnosed with non-traumatic osteonecrosis in index side by plain radiography and asymptomatic contralateral sides with normal plain radiography evaluated for non-traumatic femoral head osteonecrosis were included in the analysis. We evaluated both hips of individual patient by MRI to determine the incidence, staging, and extension area of osteonecrosis.
Thirty-two patients with index femoral head osteonecrosis and non-traumatic asymptomatic contralateral femoral head were studied. Average age of these patients was 46.38 years. The most common risk factors were alcohol (78.12%) and corticosteroid use (18.75%). Osteonecrosis of the contralateral femoral head (ONFH) was found in 22 patients (68.75%). These hips were in stage VI (87.5%) with 99.05% extension area of osteonecrosis, large extension, C- location, and mix intensity of MRI on index side. We found stage I in all patients (100%), 80.62% extension area of osteonecrosis, large extension, C-location and mix intensity of MRI on ONFH at contralateral side with normal plain radiographic.
We found the high incidence rate and high extension area of asymptomatic osteonecrosis of the contralateral femoral head of the hip in high-risk patient. This result supported that silent aggressive disease can rapidly progress to advanced stage in a short time. Early detection of osteonecrosis in contralateral hip by MRI is considered a clinically necessary procedure in high-risk patients with unilateral hip osteonecrosis.
研究高危患者群体中对侧股骨头非创伤性无症状骨坏死(ONFH)的发生率及病变范围。
采用横断面设计。我们研究了2007年1月至2008年12月期间在孔敬医院骨科就诊的患者。分析仅纳入通过X线平片诊断为患侧非创伤性骨坏死且对侧无症状、X线平片正常的高危患者,并对其双侧髋关节进行MRI检查,以确定骨坏死的发生率、分期及病变范围。
研究了32例患侧股骨头骨坏死且对侧非创伤性无症状股骨头的患者。这些患者的平均年龄为46.38岁。最常见的危险因素是饮酒(78.12%)和使用皮质类固醇(18.75%)。22例患者(68.75%)发现对侧股骨头骨坏死(ONFH)。这些髋关节处于VI期(87.5%),骨坏死病变范围达99.05%,范围大,位于C区,患侧MRI表现为混合信号强度。对侧X线平片正常的ONFH患者均为I期(100%),骨坏死病变范围为80.62%,范围大,位于C区,MRI表现为混合信号强度。
我们发现高危患者髋关节对侧无症状骨坏死的发生率及病变范围较高。这一结果支持了隐匿性侵袭性疾病可在短时间内迅速进展至晚期。对于单侧髋关节骨坏死的高危患者,通过MRI早期检测对侧髋关节骨坏死被认为是一项临床必要的检查。