Rees Jonathan
Practitioner. 2009 Dec;253(1724):5, 3.
BPH affects 70% of men aged 60-69 and 80% of those aged 80 and above. Recently, an association between BPH and metabolic dysfunction has been postulated, suggesting links between factors that increase the risk of CVD with the risk of BPH and LUTS. As modifiable lifestyle factors play a major role in systemic metabolic disturbance and CVD, similar lifestyle factors may modify the risk of LUTS/BPH. Moderate alcohol intake reduces the risk of CVD. A meta-analysis looked at alcohol intake, BPH and LUTS. Alcohol intake was stratified into six levels, from < or = 5 g/day to > 36 g/day. Consumption of alcohol was found to decrease the likelihood of BPH in all six strata, but not LUTS. Compared with no alcohol, an alcohol intake of > or = 36 g/day was associated with a 35% decreased likelihood of BPH (OR 0.65).
良性前列腺增生影响70%的60 - 69岁男性以及80%的80岁及以上男性。最近，有人提出良性前列腺增生与代谢功能障碍之间存在关联，这表明增加心血管疾病风险的因素与良性前列腺增生及下尿路症状的风险之间存在联系。由于可改变的生活方式因素在全身性代谢紊乱和心血管疾病中起主要作用，类似的生活方式因素可能会改变下尿路症状/良性前列腺增生的风险。适度饮酒可降低心血管疾病风险。一项荟萃分析研究了酒精摄入量、良性前列腺增生和下尿路症状。酒精摄入量被分为六个水平，从每天≤5克到＞36克。结果发现，在所有六个分层中，饮酒都会降低患良性前列腺增生的可能性，但不会降低下尿路症状的可能性。与不饮酒相比，每天饮酒≥36克与患良性前列腺增生的可能性降低35%相关（比值比为0.65）。
