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槲寄生中的黄酮醇和二苯丙烷糖苷及糖苷酰酯。

Flavanone and diphenylpropane glycosides and glycosidic acyl esters from Viscum articulatum.

机构信息

Division of Herbal Drugs and Natural Products, National Research Institute of Chinese Medicine, Taipei 112, Taiwan, Republic of China.

出版信息

J Nat Prod. 2010 Feb 26;73(2):109-14. doi: 10.1021/np9004294.

Abstract

Seven new compounds including three flavanone glycosides, visartisides A-C (1-3), three glycoside acyl esters, visartisides D-F (4-6), and one diphenylpropane glycoside, (4'-hydroxy-2',3',6',3''-tetramethoxy-1,3-diphenylpropane)-4''-O-beta-d-glucopyranoside (7), along with four known flavanone glycosides (8-11) were isolated from the leaves and stems of Viscum articulatum. The structure elucidation of 1-7 was based on spectroscopic data analysis. Biological evaluation showed that 1, 2, and 10 exhibited antioxidant activity using a DPPH method and that compounds 1, 3, and 11 were active in a lipopolysaccharide-induced nitric oxide assay.

摘要

从槲寄生属植物(Viscum articulatum)的叶和茎中分离得到了 7 种新化合物,包括 3 种黄烷酮糖苷,维斯塔蒂斯 A-C(1-3),3 种糖苷酰酯,维斯塔蒂斯 D-F(4-6),和 1 种二苯丙烷糖苷((4'-羟基-2',3',6',3''-四甲氧基-1,3-二苯基丙烷)-4''-O-β-d-吡喃葡萄糖苷(7),以及 4 种已知的黄烷酮糖苷(8-11)。1-7 的结构鉴定基于光谱数据分析。生物评价表明,1、2 和 10 种化合物在 DPPH 法中具有抗氧化活性,化合物 1、3 和 11 在脂多糖诱导的一氧化氮测定中具有活性。

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