Laboratory of Functional Foods and Nutraceuticals, Centro de Investigación en Alimentación y Desarrollo, A.C., Carretera a Eldorado Km. 5.5, Col. Campo El Diez, CP. 80110, Culiacán, Sinaloa, México.
Research Institute of Integrative Life Sciences, Dongguk University-Seoul, Goyang-si, 10326, Republic of Korea.
Comb Chem High Throughput Screen. 2024;27(8):1093-1110. doi: 10.2174/1386207326666230825113631.
Plants from the genus and , also known as American and European mistletoe, are a group of hemiparasitic plants traditionally used to treat many diseases. Mistletoes have a rich content of natural compounds like terpenes, alkaloids, proteins, and phenolic compounds associated with their potential medicinal properties. In this sense, mistletoes have shown antiproliferative, antioxidant, anti-inflammatory, and antimicrobial activity, which has been attributed to their phytochemical constituents. The mechanisms in which mistletoe plants act vary and depend on their phytochemical content and distribution, which in part will depend on the mistletoe species. In this sense, recent literature research is needed to visualize state of the art in the ethnopharmacological potential of mistletoe. Thus, this literature review aims to systematically report recent studies (2010-2023) on the phytochemical characterization and bioactive studies of mistletoe plants, mainly the and genera. We gather recent information of 140 references selected in our research. Here we report that although there are several bioactivity studies of mistletoe species, bioavailability studies are still scarce, and the precise mechanisms of action are not fully known. We encourage that further studies include a systematic strategy to cover these areas of opportunity.
和 属植物，也被称为美洲和欧洲槲寄生，是一组半寄生植物，传统上用于治疗许多疾病。槲寄生含有丰富的天然化合物，如萜类、生物碱、蛋白质和酚类化合物，这些化合物与它们的潜在药用特性有关。从这个意义上说，槲寄生表现出抗增殖、抗氧化、抗炎和抗菌活性，这归因于它们的植物化学成分。槲寄生植物的作用机制各不相同，取决于它们的植物化学物质含量和分布，而这在一定程度上又取决于槲寄生的种类。在这个意义上，需要对槲寄生的民族药理学潜力进行最新文献研究，以了解最新的研究进展。因此，本文献综述旨在系统地报告 2010 年至 2023 年期间关于槲寄生植物的植物化学特征和生物活性研究的最新研究，主要是 和 属。我们收集了在我们的研究中选择的 140 篇参考文献的最新信息。在这里，我们报告说，尽管有几项关于槲寄生物种的生物活性研究，但生物利用度研究仍然很少，作用的确切机制尚不完全清楚。我们鼓励进一步的研究包括一个系统的策略来涵盖这些机会领域。
