Operational Directorate of Bacterial Diseases, Veterinary and Agrochemical Research Centre (VAR/CODA/CERVA), Ukkel, Belgium.
Epidemiol Infect. 2010 May;138(5):606-25. doi: 10.1017/S0950268809991567. Epub 2010 Feb 2.
Until recently, reports on methicillin-resistant Staphylococcus aureus (MRSA) in food production animals were mainly limited to occasional detections in dairy cattle mastitis. However, since 2005 a MRSA clone, CC398, has been reported colonizing pigs, veal calves and broiler chickens and infecting dairy cows. Many aspects of its prevalence in pigs remain unclear. In other livestock, colonizing capacity and reservoir status still require elucidation. MRSA CC398 has also been detected in meat, but, as for other MRSA, the risk this poses is somewhat unclear. Currently, the most worrying aspect of MRSA CC398 appears to be its capacity to spread to humans. This might complicate MRSA control measures in human healthcare, urging research into risk factors and transmission routes. Although infections with MRSA CC398 are much less reported than carriage, more investigation into its pathogenic potential is required. Moreover, the origin and evolution of this clone remain unknown.
直到最近，关于食品生产动物中耐甲氧西林金黄色葡萄球菌（MRSA）的报告主要局限于在奶牛乳腺炎中偶尔检出。然而，自 2005 年以来，一个 MRSA 克隆株 CC398 已被报道定植于猪、小牛肉牛犊和肉鸡，并感染奶牛。其在猪中的流行情况的许多方面仍不清楚。在其他牲畜中，定植能力和储菌状态仍需要阐明。CC398 型 MRSA 也已在肉类中检出，但与其他 MRSA 一样，其带来的风险尚不清楚。目前，CC398 型 MRSA 最令人担忧的方面似乎是其传播给人类的能力。这可能会使人类医疗保健中的 MRSA 控制措施复杂化，促使研究其危险因素和传播途径。虽然 CC398 型 MRSA 的感染报告比定植少得多，但需要对其致病潜力进行更多的调查。此外，该克隆的起源和进化仍不清楚。
