Post-Graduation Program in Medical Sciences, School of Medicine, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil.
Nutr Res Rev. 2010 Jun;23(1):155-68. doi: 10.1017/S0954422410000016. Epub 2010 Feb 2.
The present review has the objective of summarising chronobiological aspects of shift work and obesity. There was a systematic search in PubMed databases, using the following descriptors: shift work; obesity; biological clock. Shift work is extremely frequent in several services and industries, in order to systematise the needs for flexibility of the workforce, necessary to optimise productivity and business competitiveness. In developing countries, this population represents a considerable contingent workforce. Recently, studies showed that overweight and obesity are more prevalent in shift workers than day workers. In addition, the literature shows that shift workers seem to gain weight more often than those workers submitted to a usual work day. In conclusion, there is considerable epidemiological evidence that shift work is associated with increased risk for obesity, diabetes and CVD, perhaps as a result of physiological maladaptation to chronically sleeping and eating at abnormal circadian times. The impact of shift work on metabolism supports a possible pathway to the development of obesity and its co-morbities. The present review demonstrated the adverse cardiometabolic implications of circadian misalignment, as occurs chronically with shift workers.
本综述旨在总结轮班工作和肥胖的生物节律学方面。我们在 PubMed 数据库中进行了系统检索，使用了以下术语：轮班工作；肥胖；生物钟。为了使劳动力的灵活性需求系统化，以优化生产力和企业竞争力，在许多服务和行业中，轮班工作极其频繁。在发展中国家，这部分人群代表了相当数量的劳动力。最近的研究表明，与白班工人相比，超重和肥胖在轮班工人中更为普遍。此外，文献表明，轮班工人似乎比那些每天按常规工作时间工作的工人更容易增重。总之，有大量的流行病学证据表明，轮班工作与肥胖、糖尿病和心血管疾病的风险增加有关，这可能是由于生理上长期适应在异常的昼夜节律时间睡眠和进食而导致的。轮班工作对新陈代谢的影响支持了肥胖及其合并症发展的一种可能途径。本综述表明，昼夜节律失调会对心血管代谢产生不良影响，这种情况在轮班工人中经常发生。
