Centre for Sports Medicine and Human Performance, Brunel University, Uxbridge, West London, UK.
Endocrinol Metab Clin North Am. 2010 Mar;39(1):201-15, xi. doi: 10.1016/j.ecl.2009.10.010.
Hugh Montgomery's discovery of the first of more than 239 fitness genes together with rapid advances in human gene therapy have created a prospect of using genes, genetic elements, and cells that have the capacity to enhance athletic performance (to paraphrase the World Anti-Doping Agency's definition of gene doping). This brief overview covers the main areas of interface between genetics and sport, attempts to provide a context against which gene doping may be viewed, and predicts a futuristic legitimate use of genomic (and possibly epigenetic) information in sport.
休·蒙哥马利发现了 239 多个以上的适应能力基因中的第一个，再加上人类基因治疗的迅速进步，为利用具有提高运动表现能力的基因、遗传因子和细胞创造了前景（用世界反兴奋剂机构对基因兴奋剂的定义来转述）。本简要综述涵盖了遗传学与运动之间的主要接口领域，试图提供一个可以观察基因兴奋剂的背景，并预测基因组（可能还有表观遗传）信息在运动中的未来合法用途。
