Hong Kong Poison Information Centre, United Christian Hospital, Kwun Tong, Hong Kong.
Hong Kong Med J. 2010 Feb;16(1):6-11.
To study the acute clinical presentations of ketamine abusers in Hong Kong.
Retrospective chart review.
Fifteen accident and emergency departments in Hong Kong.
Consultations associated with recent ketamine use either confirmed by history or urine test were searched for from the database of the Hospital Authority Hong Kong Poison Information Centre from 1 July 2005 to 30 June 2008. Their medical records and investigation results were analysed.
A total of 233 records of ketamine use were included for review. Patient ages ranged from 13 to 60, with a median of 22 years, and the male-to-female ratio being 2.1:1. The most common symptoms of ketamine misuse were impaired consciousness (45%), abdominal pain (21%), lower urinary tract symptoms (12%), and dizziness (12%). The most common abnormal physical findings were high blood pressure (40%), followed by tachycardia (39%), abdominal tenderness (18%), and white powder in the nostrils (17%).
Most ketamine abusers presented acutely with transient central nervous system depression, abdominal pain, or lower urinary tract symptoms. Clinicians should be alert to the typical age-group, signs and symptoms of such abusers presenting in an acute medical setting.
研究香港氯胺酮滥用者的急性临床特征。
回顾性病历分析。
香港 15 家急救中心。
从 2005 年 7 月 1 日至 2008 年 6 月 30 日，检索香港医院管理局中毒资料中心的数据库，寻找最近使用氯胺酮且病史或尿液检查证实的中毒咨询记录。分析其病历和调查结果。
共纳入 233 例氯胺酮使用记录进行回顾。患者年龄 13 至 60 岁，中位数 22 岁，男女比例为 2.1:1。氯胺酮滥用最常见的症状为意识障碍（45%）、腹痛（21%）、下尿路症状（12%）和头晕（12%）。最常见的异常体检发现为高血压（40%），其次为心动过速（39%）、腹部压痛（18%）和鼻内有白色粉末（17%）。
大多数氯胺酮滥用者急性发作时表现为短暂的中枢神经系统抑制、腹痛或下尿路症状。在急性医疗环境中，临床医生应警惕此类滥用者的典型年龄组、体征和症状。
