Hong Kong Poison Information Centre, K3A, United Christian Hospital, 130 Hip Wo Street, Kwun Tong, Hong Kong, SAR, People's Republic of China.
J Med Toxicol. 2012 Sep;8(3):267-70. doi: 10.1007/s13181-012-0229-z.
Ketamine has been the commonest abusive substance used by Hong Kong teenager since 2005. It is also the fourth commonest poison encountered in Hong Kong Poison Information Centre (HKPIC) poisoning data in 2010. From June 2008 to July 2011, HKPIC managed 188 and 96 cases of acute and chronic ketamine poisoning, respectively, which reflect its acute and chronic toxicity pattern. Demographically, there is a male predominance, and the majority is between the ages of 10-39. For the acute cases, 48 % presented with neurological features such as confusion, drowsiness, or transient loss of consciousness which usually subside with supportive care in a few hours. For the chronic cases, 92 % of them presented with features of ketamine cystitis while about 66 % presented with chronic abdominal pain. The current understanding of ketamine cystitis and chronic abdominal pain will be reviewed. Management is primarily symptomatic measures and most importantly abstinence from ketamine use.
自 2005 年以来，氯胺酮已成为香港青少年最常滥用的物质。它也是香港中毒咨询中心（HKPIC）2010 年中毒数据中第四种最常见的毒物。从 2008 年 6 月至 2011 年 7 月，HKPIC 分别管理了 188 例和 96 例急性和慢性氯胺酮中毒病例，反映了其急性和慢性毒性模式。从人口统计学上看，男性居多，年龄多在 10-39 岁之间。对于急性病例，48%出现神经症状，如意识模糊、嗜睡或短暂意识丧失，通常在数小时内支持性治疗后缓解。对于慢性病例，92%的患者出现氯胺酮膀胱炎的特征，约 66%的患者出现慢性腹痛。将对氯胺酮膀胱炎和慢性腹痛的现有认识进行综述。治疗主要是对症治疗，最重要的是戒除氯胺酮使用。
