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新诊断糖尿病患者的血脂异常:2006年雅加达原发性非传染性疾病危险因素监测

Dyslipidemia in newly diagnosed diabetes mellitus: the Jakarta primary non-communicable disease risk factors surveillance 2006.

作者信息

Soebardi Suharko, Purnamasari Dyah, Oemardi Maryantoro, Soewondo Pradana, Waspadji Sarwono, Soegondo Sidartawan

机构信息

Department of Medicine, University of Indonesia, Jakarta Pusat 10430, Indonesia.

出版信息

Acta Med Indones. 2009 Oct;41(4):186-90.

PMID:20124614
Abstract

AIM

To obtain the prevalence of dyslipidemia and other cardiovascular risk factors in subjects with undiagnosed DM in Jakarta, Indonesia.

METHODS

Data were obtained from surveillance of primary non-communicable disease in five regions in Jakarta, Indonesia, conducted in 2006. Targeting for 1,800 samples, we performed a purposive and simple random sampling of subjects within the age range of 25-64 years old in selected sampling areas, and stratified random sampling by adjusting to age and sex within those selected sampling areas. DM was diagnosed according to WHO criteria after an oral glucose test, i.e fasting blood glucose > or = 126 mg/dL or post loading blood glucose > or = 200 mg/dL and subjects had no history of DM. Dyslipidemia was diagnosed if triglyceride > or = 150 mg/dL, HDL-cholesterol in men < 40 mg/dL or < 50 mg/dL in women and total cholesterol > or = 200 mg/dL.

RESULTS

From 1,591 subjects, comprising 640 men and 951 women, the prevalence of newly diagnosed DM is 8.4%. Among this subjects, the prevalences of hypercholesterolemia, hypertriglyceridemia and low HDL-cholesterol are 66.1 (OR 2.28; P=0.004), 54.3 (OR 3.02; P= 0.0001) and 38.6% (OR 2.27; P=0.009) respectively. The prevalence of dyslipidemia in subjects with newly diagnosed DM remains higher among all age groups than that in subjects without DM.

CONCLUSION

the prevalence of dyslipidemia among subjects with newly diagnosed DM is higher than that in subjects without DM.

摘要

目的

获取印度尼西亚雅加达未确诊糖尿病患者的血脂异常及其他心血管危险因素的患病率。

方法

数据来自2006年在印度尼西亚雅加达五个地区开展的原发性非传染性疾病监测。以1800个样本为目标,我们在选定的抽样区域对25 - 64岁年龄段的受试者进行了立意抽样和简单随机抽样,并在这些选定的抽样区域内按年龄和性别进行分层随机抽样。口服葡萄糖耐量试验后,根据世界卫生组织标准诊断糖尿病,即空腹血糖≥126mg/dL或服糖后血糖≥200mg/dL且受试者无糖尿病病史。若甘油三酯≥150mg/dL、男性高密度脂蛋白胆固醇<40mg/dL或女性<50mg/dL且总胆固醇≥200mg/dL,则诊断为血脂异常。

结果

在1591名受试者中,包括640名男性和951名女性,新诊断糖尿病的患病率为8.4%。在这些受试者中,高胆固醇血症、高甘油三酯血症和低高密度脂蛋白胆固醇血症的患病率分别为66.1%(比值比2.28;P = 0.004)、54.3%(比值比3.02;P = 0.0001)和38.6%(比值比2.27;P = 0.009)。新诊断糖尿病患者中血脂异常的患病率在所有年龄组中均高于无糖尿病患者。

结论

新诊断糖尿病患者中血脂异常的患病率高于无糖尿病患者。

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