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能谱对高能电子束剂量分布计算的影响。

Effects of energy spectrum on dose distribution calculations for high energy electron beams.

作者信息

Toutaoui Abdelkader, Khelassi-Toutaoui Nadia, Brahimi Zakia, Chami Ahmed Chafik

机构信息

Département de Physique Médicale, Center de Recherche Nucléaire d'Alger; 2 Bd Frantz Fanon BP399 Alger RP, Algiers, Algeria.

出版信息

J Med Phys. 2009 Jan;34(1):4-11. doi: 10.4103/0971-6203.48715.

Abstract

In an early work we have demonstrated the possibility of using Monte Carlo generated pencil beams for 3D electron beam dose calculations. However, in this model the electron beam was considered as monoenergetic and the effects of the energy spectrum were taken into account by correction factors, derived from measuring central-axis depth dose curves. In the present model, the electron beam is considered as polyenergetic and the pencil beam distribution of a clinical electron beam, of a given nominal energy, is represented as a linear combination of Monte Carlo monoenergetic pencil beams. The coefficients of the linear combination describe the energy spectrum of the clinical electron beam, and are chosen to provide the best-fit between the calculated and measured central axis depth dose, in water. The energy spectrum is determined by the constrained least square method. The angular distribution of the clinical electron beam is determined by in-air penumbra measurements. The predictions of this algorithm agree very well with the measurements in the region near the surface, and the discrepancies between the measured and calculated dose distributions, behind 3D heterogeneities, are reduced to less than 10%. We have demonstrated a new algorithm for 3D electron beam dose calculations, which takes into account the energy spectra. Results indicate that the use of this algorithm leads to a better modeling of dose distributions downstream, from complex heterogeneities.

摘要

在早期的一项工作中,我们已经证明了使用蒙特卡罗生成的笔形束进行三维电子束剂量计算的可能性。然而,在该模型中,电子束被视为单能的,并且通过从测量中心轴深度剂量曲线得出的校正因子来考虑能谱的影响。在当前模型中,电子束被视为多能的,并且给定标称能量的临床电子束的笔形束分布表示为蒙特卡罗单能笔形束的线性组合。线性组合的系数描述了临床电子束的能谱,并被选择以在水中计算的和测量的中心轴深度剂量之间提供最佳拟合。能谱通过约束最小二乘法确定。临床电子束的角分布通过空气中半值宽测量来确定。该算法的预测结果与表面附近区域的测量结果非常吻合,并且在三维不均匀性之后测量的和计算的剂量分布之间的差异减小到小于10%。我们已经展示了一种用于三维电子束剂量计算的新算法,该算法考虑了能谱。结果表明,使用该算法可以更好地模拟复杂不均匀性下游的剂量分布。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbc6/2804147/a921db8d34de/JMP-34-4-g001.jpg

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