Department of Nutrition and Food Sciences, University of Rhode Island, Ranger Hall, Kingston, Rhode Island 02881, USA.
J Nutr Health Aging. 2010 Feb;14(2):168-72. doi: 10.1007/s12603-010-0030-0.
The aim of this study was to compare standard lipid profile, reported dietary intake, and physical activity in older adults who reported taking or not taking a lipid-lowering medication, namely statins.
Cross-sectional study utilizing baseline data collected from a subsample of a larger randomized clinical trial, The Study of Exercise and Nutrition in Older Rhode Islanders (SENIOR) Project.
A total of 115 participants, 33 males and 82 females, over the age of 60, community-dwelling, primarily retired, and from East Providence, Rhode Island and surrounding communities in Rhode Island and Massachusetts.
Height and weight were measured and used to calculate body mass index. Waist circumference was measured. Medical history and medication use surveys were completed. Dietary assessment was done via three 24 hour recalls using NDS-R. The Yale Physical Activity Survey was used to determine energy expenditure during exercise and a physical activity summary score. Fasting blood samples were obtained to determine lipid profile.
37 participants (32.2%) reported taking lipid-lowering medication, statins exclusively, and 78 (67.8%) reported not taking any lipid-lowering medication. Participants who reported taking statins had better lipid profiles than those participants who reported not taking statins but had significantly lower intakes of vitamin B12, vitamin K, calcium, and potassium. There were no differences between groups on reported physical activity. However, the mean intakes for both groups did not meet the Dietary Reference Intakes for multiple nutrients.
Older adults need additional education on the importance of lifestyle changes in reducing CHD risk, whether taking lipid-lowering medications or not.
本研究旨在比较服用或未服用降脂药物(即他汀类药物)的老年人的标准血脂谱、报告的饮食摄入量和身体活动情况。
利用较大的随机临床试验“罗德岛老年运动与营养研究(SENIOR)项目”的子样本中收集的基线数据进行的横断面研究。
共有 115 名参与者,33 名男性和 82 名女性,年龄在 60 岁以上,居住在社区,主要是退休人员,来自罗德岛州东普罗维登斯及其周围的罗德岛州和马萨诸塞州社区。
测量身高和体重,并用于计算体重指数。测量腰围。完成病史和用药情况调查。通过 NDS-R 进行三次 24 小时回顾来进行饮食评估。使用耶鲁体力活动调查来确定运动期间的能量消耗和体力活动综合得分。抽取空腹血样以确定血脂谱。
37 名参与者(32.2%)报告服用降脂药物,即他汀类药物,78 名参与者(67.8%)报告未服用任何降脂药物。服用他汀类药物的参与者的血脂谱优于未服用他汀类药物的参与者,但他们的维生素 B12、维生素 K、钙和钾摄入量明显较低。两组在报告的身体活动方面没有差异。然而,两组的平均摄入量均未达到多种营养素的膳食参考摄入量。
无论是否服用降脂药物,老年人都需要更多关于生活方式改变在降低 CHD 风险方面的重要性的教育。