China Medical University, Taichung, Taiwan.
Am J Chin Med. 2010;38(1):205-18. doi: 10.1142/S0192415X10007762.
The perfect ginseng radix is collected when the ginseng root reaches a cultivation age of six years; this ensures the best mass quality and consistency of the plant's essential bioactive components. Since traditional means of authentication via physical appearance or smell are hardly reliable, an efficient analytical method that can determine the real cultivation age of dried ginseng radix in commercial products, especially ginseng products of various dosage forms, is urgently required. In the present study, chemical fingerprint by (1)H-NMR spectroscopy was used on dried ginseng radix samples with cultivation ages ranging from 1-6 years. The resulting dataset was then analyzed by using principle component analysis and cluster analysis to build up a distributive model that allows the identification of the real cultivation age of the ginseng radix based on a plant metabolomic strategy. This quality surveillance method was able to clearly discriminate the 6 years old ginseng radix from the other ages, and could be applied on the evaluation of the real cultivation age for the various dried white ginseng radix samples and commercial products accurately.
当人参根达到六年的栽培年龄时，就可以采集到完美的人参根；这确保了植物的最佳质量和必需生物活性成分的一致性。由于传统的通过外观或气味进行认证的方法几乎不可靠，因此迫切需要一种有效的分析方法来确定商业产品中（尤其是各种剂型的人参产品）干人参根的实际栽培年龄。在本研究中，使用（1）H-NMR 光谱对栽培年龄为 1-6 年的干人参根样本进行了化学指纹图谱分析。然后，使用主成分分析和聚类分析对所得数据集进行分析，建立了一个分布模型，该模型可以基于植物代谢组学策略来识别人参根的实际栽培年龄。该质量监测方法能够清晰地区分 6 年生的人参根与其他年龄的人参根，并且可以准确地应用于各种干白参根样本和商业产品的实际栽培年龄的评估。
