Babaye-Nazhad S, Amirnia M, Alikhah H, Khodaeyani E, Atapour N
Department of Dermatology, Sina Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.
Pak J Biol Sci. 2009 Nov 1;12(21):1408-14. doi: 10.3923/pjbs.2009.1408.1414.
The aim of this study was to evaluate the intact margin after surgery regarding common method with consideration of 4 mm safe margin. Fifty patients with basal cell carcinoma operated in Tabriz Sina hospital, were chosen randomly and pathological report of these patients after surgery was evaluated with consideration of presence of intact margin. In pathologic report before operation of these patients, Basal cell carcinoma was certified. Also, brief data of these patients history was studied from present cases. Forty eight of 50 (96%) patients had intact margin after surgery and just in two patients (4%), lesion was excised insufficiently and they had involved margin. With brief study of patients' history, most of them had advanced ages and the most common site of tumor presentation was head and neck. The most of these patients had exposure with so much sun light that was accounted an important etiology. With comparison of mentioned statistical results with other reports from other countries, this rate is considered in acceptable range and surgical method is done properly in this hospital and consideration of 4 mm of tumoral margin is enough.
本研究的目的是评估采用考虑4毫米安全切缘的常用方法手术后的完整切缘情况。随机选取了50例在大不里士西纳医院接受基底细胞癌手术的患者，并根据完整切缘的存在情况评估了这些患者术后的病理报告。在这些患者术前的病理报告中，基底细胞癌得到确诊。此外，还从现有病例中研究了这些患者的简要病史资料。50例患者中有48例（96%）术后切缘完整，仅有2例（4%）切除不充分，切缘受累。通过对患者病史的简要研究，发现大多数患者年龄较大，肿瘤最常见的发生部位是头颈部。这些患者大多暴露于大量阳光下，这被认为是一个重要的病因。将上述统计结果与其他国家的其他报告进行比较，该比率被认为在可接受范围内，该医院的手术方法得当，考虑4毫米的肿瘤切缘是足够的。
