Cigna Emanuele, Tarallo Mauro, Maruccia Michele, Sorvillo Valentina, Pollastrini Alessia, Scuderi Nicolò
Department of Plastic and Reconstructive Surgery, Policlinico Umberto I, 00161 Rome, Italy.
J Skin Cancer. 2011;2011:476362. doi: 10.1155/2011/476362. Epub 2010 Dec 1.
Introduction. Basal cell carcinoma (BCC) is a locally invasive malignant epidermal tumour. Incidence is increasing by 10% per year; incidence of metastases is minimal, but relapses are frequent (40%-50%). The complete excision of the BCC allows reduction of relapse. Materials and Methods. The study cohort consists of 1123 patients underwent surgery for basal cell carcinoma between 1999 and 2009. Patient and tumor characteristics recorded are: age; gender; localization (head and neck, trunk, and upper and lower extremities), tumor size, excisional margins adopted, and relapses. Results. The study considered a group of 1123 patients affected by basal cell carcinoma. Relapses occurred in 30 cases (2,67%), 27 out of 30 relapses occurred in noble areas, where peripheral margin was <3 mm. Incompletely excised basal cell carcinoma occurred in 21 patients (1,87%) and were treated with an additional excision. Discussion. Although guidelines indicate 3 mm peripheral margin of excision in BCC <2 cm, in our experience, a margin of less than 5 mm results in a high risk of incomplete excisions.
引言。基底细胞癌（BCC）是一种局部浸润性恶性表皮肿瘤。发病率每年以10%的速度增长；转移发生率极低，但复发频繁（40%-50%）。完整切除基底细胞癌可降低复发率。材料与方法。研究队列包括1999年至2009年间接受基底细胞癌手术的1123例患者。记录的患者和肿瘤特征包括：年龄、性别、部位（头颈部、躯干、上下肢）、肿瘤大小、采用的切除边缘以及复发情况。结果。该研究纳入了一组1123例基底细胞癌患者。30例（2.67%）出现复发，其中30例复发中有27例发生在切缘<3 mm的头颈部等部位。21例（1.87%）基底细胞癌切除不完全，随后进行了再次切除。讨论。尽管指南指出对于直径<2 cm的基底细胞癌，切除边缘应为3 mm，但根据我们的经验，切缘小于5 mm会导致切除不完全的高风险。
