幼年特发性关节炎相关性葡萄膜炎的视网膜并发症：一项微视野计和光学相干断层扫描研究。

Retinal complications of juvenile idiopathic arthritis-related uveitis: a microperimetry and optical coherence tomography study.

机构信息

Department of Ophthalmology, Ocular Immunovirology Service, Sapienza University of Rome, Rome, Italy.

出版信息

Ocul Immunol Inflamm. 2010 Jan;18(1):54-9. doi: 10.3109/09273940903311999.

DOI:10.3109/09273940903311999

PMID:20128652

Abstract

PURPOSE

To evaluate ocular complications of juvenile idiopathic arthritis (JIA)-related uveitis; to study macular morphology and sensitivity.

METHODS

Retrospective chart review of 67 patients. Fourteen consecutive patients (24 eyes) observed from January to December 2008 were submitted to optical coherence tomography study (OCT) and microperimetry MP-1 examination.

RESULTS

Most frequent complications were posterior synechiae (63.0%), band keratopathy (53.9%), and cataract (31.8%). Posterior complications were documented in 37.0% of eyes: 13.8% macular edema, 12.0% papillitis, 6.8% epiretinal membranes, 2.5% retinal vasculitis, 1.7% retinal detachment. At OCT examination 25.0% of eyes presented macular edema; macular sensitivity by MP-1 was < or = 16.5 dB in 25.0% of eyes.

CONCLUSIONS

Visual prognosis is good despite ocular complications. Incidence of macular edema seems to be higher when using OCT. Microperimetry may represent a useful tool in detecting alteration in retinal sensitivity that may supplement visual acuity in the follow-up of macular edema.

摘要

目的

评估与幼年特发性关节炎（JIA）相关的葡萄膜炎的眼部并发症；研究黄斑形态和敏感性。

方法

对 67 例患者的病历进行回顾性分析。2008 年 1 月至 12 月期间观察到的 14 例连续患者（24 只眼）接受了光学相干断层扫描（OCT）和微视野 MP-1 检查。

结果

最常见的并发症是后粘连（63.0%）、带状角膜病变（53.9%）和白内障（31.8%）。37.0%的眼存在后发性并发症：13.8%黄斑水肿，12.0%视乳头炎，6.8%视网膜内膜，2.5%视网膜血管炎，1.7%视网膜脱离。在 OCT 检查中，25.0%的眼出现黄斑水肿；通过 MP-1 测量的黄斑敏感性<或=16.5dB 的眼占 25.0%。