Department of Ophthalmology, Ocular Immunovirology Service, Sapienza University of Rome, Rome, Italy.
Ocul Immunol Inflamm. 2010 Jan;18(1):54-9. doi: 10.3109/09273940903311999.
To evaluate ocular complications of juvenile idiopathic arthritis (JIA)-related uveitis; to study macular morphology and sensitivity.
Retrospective chart review of 67 patients. Fourteen consecutive patients (24 eyes) observed from January to December 2008 were submitted to optical coherence tomography study (OCT) and microperimetry MP-1 examination.
Most frequent complications were posterior synechiae (63.0%), band keratopathy (53.9%), and cataract (31.8%). Posterior complications were documented in 37.0% of eyes: 13.8% macular edema, 12.0% papillitis, 6.8% epiretinal membranes, 2.5% retinal vasculitis, 1.7% retinal detachment. At OCT examination 25.0% of eyes presented macular edema; macular sensitivity by MP-1 was < or = 16.5 dB in 25.0% of eyes.
Visual prognosis is good despite ocular complications. Incidence of macular edema seems to be higher when using OCT. Microperimetry may represent a useful tool in detecting alteration in retinal sensitivity that may supplement visual acuity in the follow-up of macular edema.
评估与幼年特发性关节炎（JIA）相关的葡萄膜炎的眼部并发症；研究黄斑形态和敏感性。
对 67 例患者的病历进行回顾性分析。2008 年 1 月至 12 月期间观察到的 14 例连续患者（24 只眼）接受了光学相干断层扫描（OCT）和微视野 MP-1 检查。
最常见的并发症是后粘连（63.0%）、带状角膜病变（53.9%）和白内障（31.8%）。37.0%的眼存在后发性并发症：13.8%黄斑水肿，12.0%视乳头炎，6.8%视网膜内膜，2.5%视网膜血管炎，1.7%视网膜脱离。在 OCT 检查中，25.0%的眼出现黄斑水肿；通过 MP-1 测量的黄斑敏感性<或=16.5dB 的眼占 25.0%。
尽管存在眼部并发症，但视觉预后良好。使用 OCT 似乎会导致黄斑水肿的发生率更高。微视野可能是一种有用的工具，可用于检测视网膜敏感性的改变，从而在黄斑水肿的随访中补充视力。
