[The use of mTOR inhibitors in kidney transplantation: who are the best patients and how should these inhibitors be used?].

The choice of immunosuppression treatment in the kidney transplant patient depends on many factors: a history of cutaneous tumor; immunological, vascular, and primary cytomegalovirus infection risks; delay in the graft resuming function; patient knowledge of the side effects of immunosuppressant treatments, etc. Starting from a case study, this article describes the indications and contraindications of mTOR inhibitor use in the long-term immunosuppression strategy in the kidney transplantation patient. It also discusses the delay after grafting when the mTOR inhibitors can be introduced, immediately or at a later time, and points out some advantages of mycophenolate or calcineurin inhibitor substitution with mTOR inhibitors.