Institute of Environmental Health, College of Public Health, National Taiwan University, No. 17, Xuzhou Road, Taipei 100, Taiwan.
Chemosphere. 2010 Mar;79(1):54-9. doi: 10.1016/j.chemosphere.2010.01.014. Epub 2010 Feb 2.
Furan has been demonstrated to be formed in a variety of heat processed foods. The presence of furan is of potential health concern because it has been classified as 'possibly carcinogenic to humans' by the International Agency for Research on Cancer (IARC). To assess the associate risks from possible exposures in Taiwan, headspace solid-phase microextraction (HS-SPME) coupled with gas chromatography/mass spectrometer (GC/MS) was used to determine furan in a variety of food samples. Due to matrix effects, standard addition method was selected to be performed in this study. More than 100 processed foods were analyzed, and the results showed that the concentrations of furan ranged from 0.4ngg(-1) to 150ngg(-1) in various kinds of samples. Higher furan levels were found principally in the categories of baby foods, coffees, sauces and broths. Exposures from different food varieties were also estimated. As for adults in Taiwan, the average daily intakes of furan were estimated to be 299.89ngkg(-1) body weight d(-1) for male, and 177.18ngkg(-1) body weight d(-1) for female. For a 6-month-old baby, the daily intake was estimated to be 0.05-0.56, and 0.11-3.42microgkg(-1) body weight d(-1) from infant formula and baby food, respectively. To avoid possible exposure, safety precautions such as heating in an open can and applying stirring are recommended to lower the furan level in foods.
呋喃已被证明存在于多种热加工食品中。由于其被国际癌症研究机构(IARC)归类为“可能对人类致癌”,因此其存在对健康有潜在的影响。为了评估在台湾可能暴露于呋喃的相关风险,本研究采用顶空固相微萃取(HS-SPME)与气相色谱/质谱联用(GC/MS)技术对多种食品中的呋喃进行了检测。由于基质效应,本研究选择了标准添加法。分析了 100 多种加工食品,结果表明,各种样品中呋喃的浓度范围为 0.4ngg(-1)至 150ngg(-1)。在婴儿食品、咖啡、酱汁和肉汤等类别中发现了更高水平的呋喃。还估计了不同食品种类的暴露情况。对于台湾的成年人,男性的平均日摄入量为 299.89ngkg(-1)体重 d(-1),女性为 177.18ngkg(-1)体重 d(-1)。对于 6 个月大的婴儿,其日摄入量估计分别为 0.05-0.56μgkg(-1)和 0.11-3.42μgkg(-1),来自婴儿配方奶粉和婴儿食品。为避免可能的暴露,建议采取安全预防措施,如在敞开的罐头中加热和搅拌,以降低食品中的呋喃含量。